Daily Archives: March 31, 2022
WHO Global genomic surveillance strategy for pathogens with pandemic and epidemic potential 2022–2032.
31 Mar, 2022 | 08:45h | UTCNews Release: WHO releases 10-year strategy for genomic surveillance of pathogens – World Health Organization
Commentary on Twitter (thread – click for more)
? Today @WHO published the Global Genomic Surveillance Strategy for Pathogens with Pandemic and Epidemic Potential (2022–2032)
Ambitious, comprehensive, strategic and necessary.
Short thread ⬇️https://t.co/98NMgMhbL6
— Maria Van Kerkhove (@mvankerkhove) March 30, 2022
WHO recommendations on maternal and newborn care for a positive postnatal experience.
31 Mar, 2022 | 08:47h | UTCNews Release: WHO urges quality care for women and newborns in critical first weeks after childbirth – World Health Organization
Commentary: Postnatal care: WHO highlights urgency of physical and mental support – The BMJ
RCT: Early treatment with ivermectin does not improve outcomes in patients with Covid-19.
31 Mar, 2022 | 08:41h | UTCCommentary: Ivermectin does not prevent COVID-19 hospitalization, a new study says – NPR
Commentary on Twitter
Ivermectin: the largest randomized, double-blind trial yet conducted, with early treatment, indicates there is no difference compared with placebo. It doesn't work. Period. https://t.co/wiFygjRgkk
just published @NEJM pic.twitter.com/uZ0mMZnO0E— Eric Topol (@EricTopol) March 30, 2022
RCT: Early outpatient treatment with convalescent plasma reduces the risk of hospitalization in patients with Covid-19.
31 Mar, 2022 | 08:39h | UTCEarly Outpatient Treatment for Covid-19 with Convalescent Plasma – New England Journal of Medicine
Commentaries:
Early Use of High-Titer Plasma Reduced COVID Hospitalizations— Randomized trial that influenced indication shows benefits in a mostly unvaccinated population – MedPage Today (free registration required)
Commentary on Twitter
Fewer recipients of convalescent plasma had progression of Covid-19–associated illness leading to hospitalization. https://t.co/joa9ajpAcd pic.twitter.com/mHTnEHYN2O
— NEJM (@NEJM) March 30, 2022
USPSTF Draft Recommendation Statement: the current evidence is insufficient to recommend screening for obstructive sleep apnea in asymptomatic individuals.
31 Mar, 2022 | 08:42h | UTCCommentary: USPSTF: Evidence Lacking for OSA Screening in Asymptomatic Adults – HealthDay
RCT: Single-incision mini-slings for stress urinary incontinence in women.
31 Mar, 2022 | 08:35h | UTCSingle-Incision Mini-Slings for Stress Urinary Incontinence in Women – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Single-incision mini-slings effective for stress urinary incontinence in women – Healio (free registration required)
Commentary on Twitter
For stress urinary incontinence in women, mini-slings were noninferior to midurethral slings with respect to patient-reported success at 15 months. https://t.co/Ag5p2u2WZW pic.twitter.com/PcajqXTiLW
— NEJM (@NEJM) March 30, 2022
Risk of SARS-CoV-2 reinfections in children: a prospective national surveillance study in England.
31 Mar, 2022 | 08:29h | UTCInvited Commentary: Importance of understanding the reinfection risk of COVID-19 in children – The Lancet Child & Adolescent Health
Commentary on Twitter
Everything we know about #SARSCoV2 tells us that first infection reduces (but doesn’t eliminate) the risk & SEVERITY of further infections, even with new variants. Here is our paper showing this with delta reinfections in kids (work on omicron reinfections in progress)? https://t.co/3gDPBHRu18
— Shamez Ladhani (@ShamezLadhani) March 30, 2022
Meta-analysis of randomized trials: Clopidogrel is better than aspirin for the secondary prevention of cardiovascular events.
31 Mar, 2022 | 08:31h | UTCCommentary: Clopidogrel Superior to ‘Divine’ Aspirin Monotherapy in Secondary Prevention – TCTMD
Commentary on Twitter
Happy to share our paper in @ESC_Journals. In this meta-analysis of randomized trials, we found that as compared with aspirin, P2Y12i was associated with 11% and 19% reduction in MACE and MI respectively. https://t.co/Y3Gstzgfu6
— Devika Aggarwal (@devikagg) March 30, 2022
Case-control study: In children 5 to 11 years of age, the Pfizer vaccine showed an effectiveness of 68% against hospitalization caused by the Omicron variant.
31 Mar, 2022 | 08:37h | UTCCommentary: COVID vaccination of children age 5-11 cut omicron hospitalizations by 68% – Children’s Hospital Boston
Commentary on Twitter
BNT162b2 vaccination reduced the risk of omicron-associated hospitalization by two thirds among children 5 to 11 years of age. https://t.co/mQcchQqbtH pic.twitter.com/Qzy8qKg1wC
— NEJM (@NEJM) March 30, 2022
M-A: Psychological interventions for chronic, non-specific low back pain.
31 Mar, 2022 | 08:20h | UTCNews Release: Study sheds light on psychological therapies for chronic low back pain – British Medical Journal
RCT: Effect of tacrolimus vs. intravenous cyclophosphamide on complete or partial response in patients with lupus nephritis.
31 Mar, 2022 | 08:18h | UTC
Commentary on Twitter
In this RCT, oral tacrolimus was noninferior to intravenous cyclophosphamide for initial therapy of active lupus nephritis, with a more favorable safety profile. https://t.co/scz7lahVRU
— JAMA Network Open (@JAMANetworkOpen) March 30, 2022
A Narrative Review on the approach to antimicrobial use in ventilated patients with multidrug resistant organisms in respiratory samples—to treat or not to treat?
31 Mar, 2022 | 08:27h | UTC
Commentary on Twitter
Important question in clinical practice
???Fantastic Narrative Review @antibioticsmdpi
Approach to Antimicrobial Use in Ventilated Patients with MDROs in Respiratory Samples—To Treat or Not to Treat? That Is the Question #IDTwitter #MedEd #TwitteRxhttps://t.co/aSYHr9xawv pic.twitter.com/hRjqjnZqtu— Antibiotic Steward Bassam Ghanem?? (@ABsteward) March 29, 2022
Association of computed tomography screening with lung cancer stage shift and survival in the United States: quasi-experimental study.
31 Mar, 2022 | 08:23h | UTCEditorial: Screening high risk populations for lung cancer
News Release: US lung cancer screening linked to earlier diagnosis and better survival – British Medical Journal
Related:
Screening for Lung Cancer: CHEST Guideline and Expert Panel Report.
Commentary on Twitter
Increases in the early detection of lung cancer since 2014 in the US have saved an estimated 10,100 lives, but screening rates are still extremely low and disparities in access to lung cancer screening continue to exist, say researchers https://t.co/j58LfcGCKU
— The BMJ (@bmj_latest) March 31, 2022
Global burden of cutaneous melanoma in 2020 and projections to 2040.
31 Mar, 2022 | 08:11h | UTCGlobal Burden of Cutaneous Melanoma in 2020 and Projections to 2040 – JAMA Dermatology (free for a limited period)
Editorial: Melanoma Epidemiology—Pivoting to Low- and Middle-Income Countries (free for a limited period)
Commentary: Global Burden of Melanoma Considerable, Set to Rise by 2040 – HealthDay
Nature Outlook: Hepatitis B.
31 Mar, 2022 | 08:05h | UTCHomepage: Nature Outlook: Hepatitis B
Closing in on a cure for hepatitis B
Developing a cure for chronic hepatitis B requires a fresh approach
How to stop mother-to-child transmission of hepatitis B
Simplify access to hepatitis B care
Facing the challenge of eliminating hepatitis B
The global fight against hepatitis B is benefitting some parts of the world more than others
Africa’s struggle with hepatitis B
Why hepatitis B hits Aboriginal Australians especially hard
Hepatitis B and the liver cancer endgame
Research round-up: hepatitis B
Charting a new frontier in chronic hepatitis B research to improve lives worldwide
Addressing the unmet need for a functional cure for chronic hepatitis B
Cohort Study: Mortality associated with mental disorders and comorbid general medical conditions.
31 Mar, 2022 | 08:15h | UTCMortality Associated With Mental Disorders and Comorbid General Medical Conditions – JAMA Psychiatry
Commentary: People with Mental Disorders, General Comorbid Conditions Have 11-Year Reduced Life Expectancy – HCP Live
Review | Advanced heart failure: guideline-directed medical therapy, diuretics, inotropes, and palliative care.
31 Mar, 2022 | 08:09h | UTC
Rickets guidance: part II—management.
31 Mar, 2022 | 08:08h | UTCRickets guidance: part II—management – Pediatric Nephrology
Related: Rickets guidance: part I—diagnostic workup.
Podcast: Deep dive into deep neck infections in children.
31 Mar, 2022 | 07:57h | UTC#47: Deep Dive into Deep Neck Infections with Dr. Travis Crook – The Cribsiders
Opinion: The illusion of evidence based medicine.
31 Mar, 2022 | 08:00h | UTCThe illusion of evidence based medicine – The BMJ
How to design high quality acupuncture trials—a consensus informed by evidence.
31 Mar, 2022 | 08:04h | UTCHow to design high quality acupuncture trials—a consensus informed by evidence – The BMJ
Commentary on Twitter
Despite over 14 000 published randomised controlled trials in acupuncture, shortcomings in the evidence persist.
This guidance covers the challenges particular to acupuncture trials and what researchers should consider when designing onehttps://t.co/eIKTov8pHT
— The BMJ (@bmj_latest) March 30, 2022
Podcast: Neonatal acute kidney injury pearls.
31 Mar, 2022 | 07:58h | UTC#46: NephMadness 2022: Neonatal AKI – The Cribsiders
Intraoperative ultrasound in brain tumor surgery: A review and implementation guide.
31 Mar, 2022 | 07:55h | UTC
Systematic Review: The economics of vision impairment and its leading causes.
31 Mar, 2022 | 07:53h | UTCThe economics of vision impairment and its leading causes: A systematic review – EClinicalMedicine
Guidance on the need for contraception related to use of pharmaceuticals: providing information on the proper use of pharmaceuticals in patients with reproductive potential.
31 Mar, 2022 | 07:49h | UTC