Daily Archives: March 18, 2022
More data suggests reduced risks of hospitalization and death due to SARS-CoV-2 Omicron compared to the Delta variant.
18 Mar, 2022 | 09:36h | UTCInvited Commentary: Omicron: fewer adverse outcomes come with new dangers – The Lancet
Commentary on Twitter
NEW—People with SARS-CoV-2 #omicron variant less likely to be admitted to hospital or die compared to those with delta variant, indicates large English study. https://t.co/xZvH5qMRDJ pic.twitter.com/fnn7xMBYDB
— The Lancet (@TheLancet) March 17, 2022
Guideline: Management of anticoagulants and antiplatelets during acute gastrointestinal bleeding and the periendoscopic period.
18 Mar, 2022 | 09:39h | UTC
Commentary on Twitter
BREAKING ?
Antiplatelets, anticoagulants and #EndoscopyNew CPG & dissemination tool.
An @AmCollegeGastro @CanGastroAssn co-production @AmJGastro and #JCAG@GriLeont @BryanGSauer @NeenaSAbrahamMD @alan_barkun @ThrombosisCan @LorenLaine2 #JenTelfordhttps://t.co/Ijs4jgOkPC pic.twitter.com/uUfN2zj3RS
— Journal of the Canadian Assn of Gastroenterology (@JCanAssnGastro) March 17, 2022
M-A: Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxemic respiratory failure.
18 Mar, 2022 | 09:32h | UTCInvited Commentary: The pandemic and the great awakening in the management of acute hypoxaemic respiratory failure – The Lancet Respiratory Medicine
Related:
RCT: Awake prone positioning reduces the need for intubation in patients with COVID-19.
Study on traumatic brain injury highlights global inequality in causes and treatment.
18 Mar, 2022 | 09:37h | UTCNews Release: Largest ever study on traumatic brain injury highlights global inequality in causes and treatment – University of Cambridge
Study finds no increased risk of rare neurological events after covid vaccination.
18 Mar, 2022 | 09:31h | UTCNews Release: Study finds no increased risk of rare neurological events after covid vaccination – BMJ Newsroom
Editorial: The neurological safety of covid-19 vaccines
RCT: Cocoa flavanol supplementation shows promise for the prevention of cardiovascular disease events.
18 Mar, 2022 | 08:54h | UTC
Commentary on Twitter (thread – click for more)
In @AJCNutrition: @HowardSesso, Dr. JoAnn Manson of @BWHDPM @BrighamWomens & colleagues report the main findings of the first ever randomized trial of a cocoa flavanol supplement on cardiovascular disease endpointshttps://t.co/0F5v8WqzdM and https://t.co/vA3wwT0Amw (1 of 5) pic.twitter.com/X08hiNUCzK
— BrighamResearch (@BrighamResearch) March 16, 2022
Maintaining oral hydration in older adults in surgical wards: a best practice implementation project.
18 Mar, 2022 | 08:50h | UTCMaintaining oral hydration in older adults in surgical wards: a best practice implementation project – JBI Evidence Implementation (free for a limited period)
Commentary on Twitter
A timely and relevant article on this #WDAD2022. It is essential that basic needs like hydration, nutrition, movement, and sleep are addressed to prevent and mitigate negative outcomes for older persons, especially those at risk for #delirium.#research #practice @JBI_EI https://t.co/YzRWMiVMKQ
— Andrea Rochon (@AndreaRochon) March 17, 2022
Using absolute risk reduction to guide the equitable distribution of COVID-19 vaccines.
18 Mar, 2022 | 09:28h | UTC
Commentary on Twitter
Using absolute risk reduction to guide the equitable distribution of COVID-19 vaccines – Analysis by Fassler et al.
What's the role of NNV?#OpenAccess
▶️ https://t.co/Bb3HlJDRXz pic.twitter.com/MPxrGNHxum
— BMJ Evidence-Based Medicine (@BMJ_EBM) March 17, 2022
Hypertension in the hospitalized patient: an update
18 Mar, 2022 | 08:18h | UTCHypertension in the hospitalized patient: An update – Nefrología
Study shows low risk of complications after ipsilateral intravenous catheter placement in breast cancer surgery patients.
18 Mar, 2022 | 08:48h | UTCIpsilateral Intravenous Catheter Placement in Breast Cancer Surgery Patients – Anesthesia & Analgesia (link to abstract – $ for full-text)
Commentary on Twitter
??? much-needed dogmalysis. I’ve seen situations where folks were afraid to even place a Bp cuff ipsilateral to prior mastectomy. this excessive fear impairs patient care. https://t.co/afjwjjseo7
— ???? ?????? ? (@PulmCrit) March 17, 2022
Assessing the magnitude of reporting bias in trials of homeopathy: a cross-sectional study and meta-analysis.
18 Mar, 2022 | 08:46h | UTCNews Release: Poor research practice suggests true impact of homeopathy may be “substantially” overestimated – BMJ Newsroom
Commentary on Twitter
Poor research practice suggests true impact of homeopathy may be “substantially” overestimated suggests @BMJ_EBM research https://t.co/5FvvJJJLX1 pic.twitter.com/2g5LWSvfYn
— BMJ (@bmj_company) March 16, 2022
Expert panel guidance and narrative review of treatment simplification of complex insulin regimens to improve outcomes in Type 2 Diabetes.
18 Mar, 2022 | 08:15h | UTC
AHA Scientific Statement: Advances in managing transition to adulthood for adolescents with congenital heart disease.
18 Mar, 2022 | 08:19h | UTCNews Release: For youth with a heart defect, shift to adult-focused care is key to health, quality of life – American Heart Association
Symptom management in patients with cirrhosis: a practical guide.
18 Mar, 2022 | 08:13h | UTCSymptom Management in Patients with Cirrhosis: a Practical Guide – Current Treatment Options in Gastroenterology (free for a limited period)
Commentary from the author on Twitter (thread – click for more)
Published today! @rrosenblattmd and I discuss treatment considerations in patients with cirrhosis, including ascites, encephalopathy, pruritus, muscle cramping, pain, depression/anxiety, fatigue, and appetite⬇️ #livertwitter #cirrhosis #ESLD https://t.co/qjPCX5YPP7
— Aly J. Kaplan, MD (@aly_kaplanMD) March 17, 2022
SEOM-GEINO clinical guideline of systemic therapy and management of brain central nervous system metastases.
18 Mar, 2022 | 08:14h | UTC
Risk of colorectal cancer is associated with lifetime excess weight.
18 Mar, 2022 | 08:07h | UTCRisk of Colorectal Cancer Associated With Lifetime Excess Weight – JAMA Oncology
Diagnostic approach to incidentally detected pancreatic cystic lesions.
18 Mar, 2022 | 08:11h | UTCRelated:
Cystic pancreatic lesions: MR imaging findings and management.
Recommendations for the management of incidental pancreatic findings in adults.
Pancreatic cystic neoplasms: a review of current recommendations for surveillance and management
Management of Pancreatic Cystic Lesions
Consensus Recommendations: Diagnosis and Surveillance of Incidental Pancreatic Cystic Lesions
Review: Pancreatic Cystic Lesions
Guidelines on pancreatic cystic neoplasms
Phase 2 RCT: Prophylactic use of garadacimab in patients with hereditary angioedema.
18 Mar, 2022 | 08:09h | UTCProphylactic use of an anti-activated factor XII monoclonal antibody, garadacimab, for patients with C1-esterase inhibitor-deficient hereditary angioedema: a randomised, double-blind, placebo-controlled, phase 2 trial – The Lancet (link to abstract – $ for full-text)
Commentary: Garadacimab significantly reduces frequency of hereditary angioedema exacerbations – Physician’s Weekly
Cohort Study: Characteristics and outcomes of Type 2 myocardial infarction.
18 Mar, 2022 | 08:05h | UTCCharacteristics and Outcomes of Type 2 Myocardial Infarction – JAMA Cardiology (link to abstract – $ for full-text)
Commentaries:
Type 2 MI Not Uncommon in the Emergency Department – TCTMD
Type 2 Myocardial Infarction: Clinical Characteristics and Outcomes – American College of Cardiology
Commentary on Twitter
Among patients presenting with acute chest discomfort to the emergency department, tachyarrhythmias and hypertension are responsible for more than two thirds of type 2 myocardial infarction and result in a lower mortality compared to other triggers. https://t.co/ODMCmOjeQO
— JAMA Cardiology (@JAMACardio) March 10, 2022
Review: Binge eating disorder.
18 Mar, 2022 | 08:03h | UTCBinge eating disorder – Nature Reviews Disease Primers (if the link is paywalled, try this one)
Infographic: Binge eating disorder (if the link is paywalled, try this one)
RCT: Efficacy of Plinabulin vs. Pegfilgrastim for prevention of docetaxel-induced neutropenia in patients with solid tumors.
18 Mar, 2022 | 08:00h | UTC
Commentary on Twitter
This RCT found that same-day plinabulin, a novel selective immunomodulating microtubule binding agent (SIMBA), is noninferior to next-day pegfilgrastim in chemotherapy-induced neutropenia prevention in patients receiving docetaxel chemotherapy. https://t.co/tUXuffISmB pic.twitter.com/LROsd3trPv
— JAMA Network Open (@JAMANetworkOpen) January 27, 2022
RCT: Oral contezolid vs. linezolid in adults with complicated skin and soft tissue infections.
18 Mar, 2022 | 07:54h | UTCA Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infections – Journal of Antimicrobial Therapy (link to abstract – $ for full-text)
Commentary on Twitter
Phase III efficacy & safety of oral contezolid Vs linezolid in adults with c.SSTIs
?Non inferior
?Interestingly:Contezolid demonstrated significant lower incidence thrombocytopenia (0% Wow vs 2.3%) & leucopenia (0.3% vs 3.4%) than linezolid
?QIDP https://t.co/wSvxUInnkZ— Antibiotic Steward Bassam Ghanem (@ABsteward) March 11, 2022
Follow-up data from 2 randomized trials: efficacy and safety of Upadacitinib in patients with moderate to severe atopic dermatitis.
18 Mar, 2022 | 07:48h | UTC
The identification and management of high blood pressure using exercise blood pressure: current evidence and practical guidance.
18 Mar, 2022 | 07:57h | UTC
Multi-disciplinary care planning of ovarian cancer in older patients.
18 Mar, 2022 | 07:55h | UTC