Daily Archives: October 24, 2021
Half doses, third doses, kids’ doses: Covid vaccine delivery goes next-level difficult.
24 Oct, 2021 | 23:52h | UTCHalf doses, third doses, kids’ doses: Covid vaccine delivery goes next-level difficult – STAT
Review: Cardiac involvement in the long-term implications of COVID-19.
24 Oct, 2021 | 23:59h | UTCCardiac involvement in the long-term implications of COVID-19 – Nature Reviews Cardiology
How you’ll know when Covid-19 has gone from “pandemic” to “endemic”.
24 Oct, 2021 | 23:53h | UTCHow you’ll know when Covid-19 has gone from “pandemic” to “endemic” – Vox
AstraZeneca vaccination not linked to reduced fertility rates and adverse birth outcomes.
24 Oct, 2021 | 23:58h | UTCFertility rates and birth outcomes after ChAdOx1 nCoV-19 (AZD1222) vaccination – The Lancet
Related:
Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
Commentary on Twitter
New research letter: Fertility rates and birth outcomes after ChAdOx1 nCoV-19 (AZD1222) vaccination. Authors analysed pregnancies occurring in four ongoing clinical trials in the UK, Brazil, and South Africa. https://t.co/hDM1olKts9@OxfordVacGroup | #COVID19 #AstraZeneca pic.twitter.com/m5qvWhPcph
— The Lancet (@TheLancet) October 23, 2021
Coronavirus: Chinese residents start receiving vaccine boosters.
24 Oct, 2021 | 23:51h | UTCCoronavirus: Chinese residents start receiving vaccine boosters – South China Morning Post
2021 Interim Guidance to Health Care Providers for Basic and Advanced Cardiac Life Support in Adults, Children, and Neonates With Suspected or Confirmed COVID-19.
24 Oct, 2021 | 23:49h | UTCCommentary: CPR on a COVID Patient: Not a Moment to Waste Looking for PPE: Updated AHA guidance says resuscitation should not be delayed by mask availability – MedPage Today (free registration required)
Commentary on Twitter (thread – click for more)
(1/2) NEW! The AHA has published its 2021 interim CPR guidance for #HCPs who treat cardiac arrest patients with suspected or confirmed #COVID19. The paper in @CircOutcomes is an update to the 2020 Interim CPR Guidance: https://t.co/tuTwWkE0dL. pic.twitter.com/B1el7dCKJM
— AHA CPR & First Aid (@HeartCPR) October 13, 2021
RCT: In comatose survivors of out-of-hospital cardiac arrest, there was no difference in mortality and neurologic outcomes with mild (target temperature of 34 °C) vs. moderate therapeutic hypothermia (target temperature of 31 °C).
24 Oct, 2021 | 23:46h | UTCEffect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The CAPITAL CHILL Randomized Clinical Trial – JAMA (free for a limited period)
Related:
Study commentary: a history of hypothermia for cardiac arrest, 2002-2021 (RIP).
Commentary on Twitter
therapeutic hypothermia after cardiac arrest is a nonbeneficial form of iatrogenesis that prolongs ICU length of stay (findings entirely consistent with TTM & TTM2). currently it should not be performed outside the context of an RCT. https://t.co/GZbpgHXWoD https://t.co/kRwRpLz6hV
— ???? ?????? ? (@PulmCrit) October 20, 2021
Guideline: Transfusion strategies in bleeding critically ill adults.
24 Oct, 2021 | 23:47h | UTC
Commentary on Twitter
Transfusion strategies in bleeding critically ill adults current evidence/research areas from @ESICM clinical practice guideline
?massive bleedings
?non‑massive bleedings
?tranexamic acid in traumatic/non‑traumatic hemorrhages
Open #FOAMcc on @yourICM
?️https://t.co/LtEzrLcaM5 pic.twitter.com/Po7eFYpdeW— Intens Care Med (@yourICM) October 22, 2021
RCT: The association of Varenicline and Nicotine patch was not better than Varenicline alone to increase smoking abstinence; there was also no difference between 24-week vs. 12-week treatment courses in abstinence rates.
24 Oct, 2021 | 23:45h | UTCEffects of Combined Varenicline With Nicotine Patch and of Extended Treatment Duration on Smoking Cessation: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Is There a Role for Combined Use of Varenicline and Nicotine Patch or Extended Treatment Duration to Enhance Smoking Cessation? – JAMA (free for a limited period)
Commentary: Varenicline Combo, Extension No Better for Quitting Smoking – HealthDay
Commentary on Twitter
Study findings do not support the use of combined varenicline plus nicotine patch therapy (vs varenicline monotherapy) or of extended treatment duration (24 vs 12 weeks) for smoking cessation https://t.co/XcQMQZgQb9
— JAMA (@JAMA_current) October 19, 2021
Middle-aged and older women are being diagnosed with Takotsubo Syndrome more frequently, up to 10 times more often, than younger women or men of any age.
24 Oct, 2021 | 23:43h | UTCNews release: Broken heart syndrome is on the rise, especially among older women – American Heart Association
Commentary: ‘Broken heart’ syndrome is on the rise in women – Cedars-Sinai Medical Center
Related:
International Expert Consensus Document on Takotsubo Syndrome
International Registry: 16.6% of Patients with Takotsubo Syndrome Have Underlying Malignancy
Systematic Review: Long-Term Prognosis and Outcome Predictors in Takotsubo Syndrome
Cohort Study: Hospital Readmission Following Takotsubo Syndrome
The cost-effectiveness of cefazolin compared to anti-staphylococcal penicillins for the treatment of methicillin-sensitive Staphylococcus aureus bacteremia.
24 Oct, 2021 | 23:41h | UTCRelated:
Meta-Analysis: Cefazolin vs. Antistaphylococcal Penicillins for MSSA Bacteremia
Commentaries on Twitter
While Cefazolin and anti-staphylococcal penicillins (ASPs), such as nafcillin, are the preferred treatments for MSSA bacteremia it looks more and more like Cefazolin is really the preferred approach. https://t.co/6FVVEWMxBY
— Daniel Griffin MD PhD (@DanielGriffinMD) October 8, 2021
New in OFID: The use of cefazolin is a cost-effective strategy for the treatment of methicillin-sensitive S. aureus bacteremia and, when clinically appropriate, results in health care cost-savings.
?: https://t.co/lRfsZdMjLJ#IDSAJournals @PaulSaxMD @DrJLi @ElMylonakis pic.twitter.com/hhzik4ppUW
— IDSA (@IDSAInfo) October 8, 2021
M-A: In patients with Staphylococcus aureus bacteremia, combination therapy does not reduce mortality and is associated with increased risks of adverse events.
24 Oct, 2021 | 23:42h | UTC
Corporate influence linked to slow implementation of public health policies globally.
24 Oct, 2021 | 23:37h | UTC
Commentary on Twitter (thread – click for more)
? Major New @LancetGH study with @hampusholmer & @sdwigley
? How has #NCD #Policy Implementation changed from 2015 – 2020?
?Which policies are being ignored?
?Country ranking
?️Regional assessment
? Corporate permeation
Summary below?…https://t.co/6pbwi5ybUM
— Luke Allen (@drlukeallen) October 20, 2021
M-A: Clinical interventions for adults with comorbid alcohol use and depressive disorders.
24 Oct, 2021 | 23:39h | UTC
Consensus statement on measures to promote equitable authorship in the publication of research from international partnerships.
24 Oct, 2021 | 23:35h | UTC
Commentary on Twitter
"Equitable authorship in international research partnerships"
In this consensus statement, we call on academic journals (& funders/employers) to ensure that an author reflexivity statement is submitted along with any manuscript from HIC-LMIC partnerships. https://t.co/IOKB04gSOm pic.twitter.com/musrVpCObz
— Ṣẹ̀yẹ Abímbọ́lá (@seyeabimbola) October 14, 2021
Extreme heat is broiling people in developing cities: New analysis finds the explosive growth of cities is helping drive dangerous conditions.
24 Oct, 2021 | 23:34h | UTCExtreme heat is broiling people in developing cities – Science
Original Study: Global urban population exposure to extreme heat – Proceedings of the National Academy of Sciences
Commentary on Twitter
People in major cities are exposed to deadly temperatures 3X more often than in the 1980s—with cities in South Asia, Africa, and the Middle East bearing the brunt, according to a new analysis of 13,000+ cities. https://t.co/C864clE4Cq
— Global Health NOW (@ghn_news) October 9, 2021