Daily Archives: August 13, 2021 | LinksMedicus Free Medical News & Perspectives

Perspective: How the pandemic now ends.

13 Aug, 2021 | 10:03h | UTC

How the pandemic now ends – The Atlantic

Commentary on Twitter (thread – click for more)

?I wrote a big piece about how Delta affects the pandemic endgame.

Many folks are upset & confused by the last month. Here's an attempt to reset expectations, lay out our goals, map the near-term future, & show how the pandemic ends–which it will. 1/https://t.co/4Ukv7zs91X

— Ed Yong (@edyong209) August 12, 2021

How do vaccinated people spread Delta? What the science says.

13 Aug, 2021 | 09:55h | UTC

How do vaccinated people spread Delta? What the science says – Nature

Opinion: Making vaccines available to other countries before offering domestic booster vaccinations.

13 Aug, 2021 | 09:48h | UTC

Making Vaccines Available to Other Countries Before Offering Domestic Booster Vaccinations – JAMA

Opinion | Could this be our first effective, inexpensive, widely available outpatient treatment for COVID-19? (It’s fluvoxamine).

13 Aug, 2021 | 09:58h | UTC

Could This Be Our First Effective, Inexpensive, Widely Available Outpatient Treatment for COVID-19? – HIV and ID Observations

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.

13 Aug, 2021 | 10:01h | UTC

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison – American Family Physician

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

Epidemiology of Multisystem Inflammatory Syndrome in Children: A Step Closer to Understanding Who, Where, and When

Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome

Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children

Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19

Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)

SR: Multisystem inflammatory syndrome in children related to COVID-19

Observational study: The combination of Immunoglobulins + Methylprednisolone was associated with a better course of fever compared to Immunoglobulins alone in Multisystem Inflammatory Syndrome in children

ACR Guidance for pediatric patients with multisystem inflammatory syndrome in children associated with SARS‐CoV‐2

New systematic review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 infection summarizes the clinical features, management, and outcomes of the disease, showing favorable outcomes for the majority of children

Opinion: Time for a smart approach to boosters.

13 Aug, 2021 | 09:51h | UTC

Time for a Smart Approach to Boosters – Think Global Health

Antibody response to COVID-19 vaccination in adults with hematologic malignant disease.

13 Aug, 2021 | 09:47h | UTC

Antibody Response to COVID-19 Vaccination in Adults With Hematologic Malignant Disease – JAMA Oncology

Commentary on Twitter

Honored Jama Onc has published our work. Please get yourself vaccinated for those in whom it does not work. Antibody Response to COVID-19 Vaccination in Adults With Hematologic Malignant Disease https://t.co/BXkUQGMmbO via @JAMAOnc part of @JAMANetwork

— Tom Ollila (@OllilaTom) August 11, 2021

How COVID-19 will change the management of other respiratory viral infections.

13 Aug, 2021 | 09:52h | UTC

How COVID-19 will change the management of other respiratory viral infections – Intensive Care Medicine

Commentary on Twitter

Still in the midst of #SARSCoV2 #pandemic, still so much to learn… but #COVID19 experience should transform approach to research on RVIs
?antiviral therapy
?corticosteroids
?specific immune modulation
?anticoagulation
?respiratory support#COVIDFOAM https://t.co/WVKRSJARvl pic.twitter.com/qMkB4tkz06

— Intens Care Med (@yourICM) August 11, 2021

Guideline: Non-surgical interventions for lumbar spinal stenosis leading to neurogenic claudication.

13 Aug, 2021 | 09:03h | UTC

Non-Surgical Interventions for Lumbar Spinal Stenosis Leading To Neurogenic Claudication: A Clinical Practice Guideline – Journal of Pain

German S3-Guideline on the treatment of Psoriasis vulgaris.

13 Aug, 2021 | 09:45h | UTC

German S3-Guideline on the treatment of Psoriasis vulgaris, adapted from EuroGuiDerm – Part 1: Treatment goals and treatment recommendations – Journal of the German Society of Dermatology

M-A: Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients.

13 Aug, 2021 | 09:01h | UTC

Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis – Intensive Care Medicine

Commentary on Twitter

Preventing #delirium in #ICU SR/NMA
?dexmedetomidine likely ⬇️ occurrence vs placebo & BDZs (moderate certainty)
?sedation-minimization strategies vs BDZs may ⬇️ (uncertain)
?DEX likely ⬇️ICU LoS vs placebo (moderate certainty) & vs antipsychotics (low)https://t.co/PWqKiyqLJz pic.twitter.com/QlANSH8icr

— Intens Care Med (@yourICM) August 13, 2021

First World Consensus Conference on Pancreas Transplantation.

13 Aug, 2021 | 09:43h | UTC

Part I – methods and results of literature search – American Journal of Transplantation

Part II – recommendations – American Journal of Transplantation

Study shows clinicians significantly overestimate the benefits of treatment to individual patients.

13 Aug, 2021 | 08:58h | UTC

Clinician Conceptualization of the Benefits of Treatments for Individual Patients – JAMA Network Open

Commentary on Twitter

All clinicians & trainees should read this study by @dr_dmorgan et al: in this survey N=542 “Clinicians consistently overestimated the chance that treatments would benefit an individual patient.”

Not by a few %age points, but overestimations of >10-20x!https://t.co/o5SSTnztgi

— Awais Aftab (@awaisaftab) August 10, 2021

Cohort study: Long-term night shift work is associated with the risk of atrial fibrillation and coronary heart disease.

13 Aug, 2021 | 08:56h | UTC

Long-term night shift work is associated with the risk of atrial fibrillation and coronary heart disease – European Heart Journal

Commentary on Twitter

Long-term night shift work is associated with the risk of atrial fibrillation and coronary heart disease.#EHJ #AF https://t.co/fd13eaDfmO pic.twitter.com/e1XmcTYcK5

— EHJ Editor-in-Chief (@ehj_ed) August 12, 2021

European guideline and expert statements on the management of narcolepsy in adults and children.

13 Aug, 2021 | 09:02h | UTC

European guideline and expert statements on the management of narcolepsy in adults and children – European Journal of Neurology

M-A of randomized trials: proton pump inhibitors for gastro-esophageal reflux disease does not improve outcomes in patients with asthma.

13 Aug, 2021 | 08:53h | UTC

Randomised trials of proton pump inhibitors for gastro-oesophageal reflux disease in patients with asthma: an updated systematic review and meta-analysis – BMJ Open

Randomized phase III trial of prophylactic cranial irradiation with or without hippocampal avoidance for small-cell lung cancer – “This trial provides the first clinical evidence that sparing the hippocampus during PCI in patients with SCLC better preserves cognitive function”.

13 Aug, 2021 | 08:54h | UTC

Randomized Phase III Trial of Prophylactic Cranial Irradiation With or Without Hippocampal Avoidance for Small-Cell Lung Cancer (PREMER): A GICOR-GOECP-SEOR Study – Journal of Clinical Oncology

RCT: Effect of sacrospinous hysteropexy with graft vs vaginal hysterectomy with uterosacral ligament suspension on treatment failure in women with uterovaginal prolapse.

13 Aug, 2021 | 08:52h | UTC

Effect of sacrospinous hysteropexy with graft vs vaginal hysterectomy with uterosacral ligament suspension on treatment failure in women with uterovaginal prolapse: 5-year results of a randomized clinical trial – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

Commentary on Twitter (video summary)

https://t.co/DvGgwjug34 #SUPeRTrial #PFDNresearch @AJOG_thegray pic.twitter.com/PDDr6NvGNV

— Pelvic Floor Disorders Network (PFDN) (@PFDNresearch) April 9, 2021