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Daily Archives: August 2, 2021

Opinion | Should pregnant women have a COVID vaccine? The evidence says it’s safe and effective.

2 Aug, 2021 | 00:28h | UTC

Should pregnant women have a COVID vaccine? The evidence says it’s safe and effective – The Conversation

 

The study behind new CDC’s mask guidance found vaccinated people can spread delta variant.

2 Aug, 2021 | 00:33h | UTC

CDC Report: Outbreak of SARS-CoV-2 Infections, Including COVID-19 Vaccine Breakthrough Infections, Associated with Large Public Gatherings — Barnstable County, Massachusetts, July 2021 – Centers for Disease Control and Prevention

Commentaries:

The Study Behind CDC’s Mask Guidance Found Vaccinated People Can Spread Delta Variant – NPR

What Delta has changed in the Covid pandemic — and what it hasn’t – STAT

 

Commentary on Twitter (thread – click for more)

 

Guideline: Clinical management of adult patients with COVID-19 Outside Intensive Care Units.

2 Aug, 2021 | 00:26h | UTC

Clinical Management of Adult Patients with COVID-19 Outside Intensive Care Units: Guidelines from the Italian Society of Anti-Infective Therapy (SITA) and the Italian Society of Pulmonology (SIP) – Infectious Diseases and Therapy

 

How the coronavirus infects cells — and why Delta is so dangerous.

2 Aug, 2021 | 00:22h | UTC

How the coronavirus infects cells — and why Delta is so dangerous – Nature

 

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – “ACOG encourages its members to enthusiastically recommend vaccination to their patients.”

2 Aug, 2021 | 00:31h | UTC

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – American College of Obstetricians and Gynecologists (ACOG) and the Society for Maternal-Fetal Medicine (SMFM)

Additional reading:

Practice Advisory: COVID-19 Vaccination Considerations for Obstetric-Gynecologic Care

COVID-19 Vaccines and Pregnancy: Conversation Guide for Clinicians

Commentaries:

Obstetrician groups recommend COVID vaccine during pregnancy – Associated Press

Statements By Obstetrics Societies Strongly Advise Covid-19 Vaccinations For Pregnant Women – Forbes

 

Commentary on Twitter

 

Post-viral effects of COVID-19 in the olfactory system and their implications.

2 Aug, 2021 | 00:24h | UTC

Post-viral effects of COVID-19 in the olfactory system and their implications – The Lancet Neurology

Related:

Study finds 96.1% of patients objectively recovered from anosmia 1 year after COVID-19 diagnosis.

Eight out of ten people hospitalized with COVID-19 develop neurological problems – the most common self-reported symptoms included headache (37%) and anosmia or ageusia (26%).

Loss of smell in mild Covid-19 cases occurs 86% of the time, study says

Management of anosmia and loss of smell in the era of Covid-19

 

What every intensivist should know about Tocilizumab.

2 Aug, 2021 | 00:25h | UTC

What every intensivist should know about Tocilizumab – Critical Care

Related:

Tocilizumab in COVID-19 therapy: who benefits, and how?

A living WHO guideline on drugs for covid-19 – interleukin-6 receptor blockers are now recommended for patients with severe or critical covid-19.

M-A: Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19 – “The 4% absolute risk reduction in mortality from 25% to 21% with IL-6 inhibition added to glucocorticoids may not translate to patients with a lower baseline mortality risk and likely do not justify the additional expense and risk for toxicities for patients hospitalized with modest oxygen requirements and a stable clinical course (from editorial)”.

RECOVERY trial: In hospitalized COVID-19 patients with hypoxia and systemic inflammation (C-reactive protein ≥75 mg/L), tocilizumab improved survival and other clinical outcomes

Secondary analysis of RCT finds Tocilizumab was beneficial to patients hospitalized with Covid-19 if CRP levels were greater than 15.0 mg/dL, but not if CRP levels were 15.0 mg/dL or less.

M-A: Tocilizumab in COVID-19 – “For hospitalized COVID-19 patients, there is some evidence that tocilizumab use may be associated with a short-term mortality benefit, but further high-quality data are required”.

 

COVID boosters for wealthy nations spark outrage.

2 Aug, 2021 | 00:21h | UTC

COVID boosters for wealthy nations spark outrage – Nature

Related: MSF: No COVID-19 booster shots anywhere before healthcare workers and vulnerable people everywhere have access – Médecins Sans Frontières/Doctors Without Borders

 

Clinical practice guidelines for the management of colonic volvulus and acute colonic pseudo-obstruction.

2 Aug, 2021 | 00:13h | UTC

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Colonic Volvulus and Acute Colonic Pseudo-Obstruction – Diseases of the Colon & Rectum

News release: American Society of Colon & Rectal Surgeons Publishes New Guidelines for Colonic Volvulus and Acute Colonic Pseudo-Obstruction

 

Scientists Grapple with Question of COVID-19 Vaccine Booster, as Some Countries Push Ahead.

2 Aug, 2021 | 00:19h | UTC

Scientists Grapple With Question of COVID-19 Vaccine Booster, as Some Countries Push Ahead – Health Policy Watch

 

Ten things to know about ten imaging studies: A preventive cardiology perspective.

2 Aug, 2021 | 00:12h | UTC

Ten things to know about ten imaging studies: A preventive cardiology perspective (“ASPC top ten imaging”) – American Journal of Preventive Cardiology

 

AHA Scientific Statement: Lower extremity peripheral artery disease: contemporary epidemiology, management gaps, and future directions.

2 Aug, 2021 | 00:17h | UTC

Lower Extremity Peripheral Artery Disease: Contemporary Epidemiology, Management Gaps, and Future Directions: A Scientific Statement From the American Heart Association – Circulation

Top Things to Know: Lower Extremity Peripheral Artery Disease: Contemporary Epidemiology, Management Gaps, and Future Directions – American Heart Association

Commentary: The Need for Improved Identification and Treatment of Peripheral Arterial Disease – American Heart Association

 

Assessment and management of peripheral arterial disease: what every cardiologist should know.

2 Aug, 2021 | 00:15h | UTC

Assessment and management of peripheral arterial disease: what every cardiologist should know – Heart

 

Commentary on Twitter

 

Ten things to know about ten cardiovascular disease risk factors.

2 Aug, 2021 | 00:11h | UTC

Ten things to know about ten cardiovascular disease risk factors – American Journal of Preventive Cardiology

 

Study: many patients with small renal masses can be safely managed with active surveillance.

2 Aug, 2021 | 00:07h | UTC

Active Surveillance for Risk Stratification of All Small Renal Masses Lacking Predefined Clinical Criteria for Intervention – The Journal of Urology

Commentary: More Data Support Active Surveillance for Small Renal Masses — Most patients avoided surgery with no metastasis, better focus on aggressive disease – MedPage Today (free registration required)

 

Investigation: FDA allows drugs without proven clinical benefit to languish for years on accelerated pathway.

2 Aug, 2021 | 00:09h | UTC

FDA allows drugs without proven clinical benefit to languish for years on accelerated pathway – The BMJ

News release: Investigation finds nearly half of drugs granted FDA ‘fast track’ approval lack proven clinical benefit – The BMJ

Commentary: Over 100 Drugs Given Speedy Approvals Still Lack Proof of Clinical Efficacy – MedPage Today (free registration required)

 

Guideline summary: A Multidisciplinary collaborative approach to retinal toxic effects screening for patients taking antimalarials.

2 Aug, 2021 | 00:03h | UTC

A Multidisciplinary Collaborative Approach to Retinal Toxic Effects Screening for Dermatology Patients Taking Antimalarials – JAMA Dermatology (free for a limited period)

Original Guidance: Joint Statement: Hydroxychloroquine use with respect to retinal toxicity

 

Does this adult patient have hypertension? the rational clinical examination systematic review.

2 Aug, 2021 | 00:05h | UTC

Does This Adult Patient Have Hypertension? The Rational Clinical Examination Systematic Review – JAMA (free for a limited period)

 

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