Daily Archives: July 8, 2021
Case series: therapeutic plasma exchange in 3 patients with vaccine-induced immune thrombotic thrombocytopenia.
8 Jul, 2021 | 09:17h | UTC
Commentary on Twitter
Three patients with severe manifestations of VITT after #COVID19 vaccination had poor response to initial therapy with anticoagulants and intravenous immune globulin. Their condition improved after therapeutic plasma exchange was initiated.
— NEJM (@NEJM) July 7, 2021
Prospective national cohort in Chile showed CoronaVac effectiveness was 65.9% for symptomatic Covid-19, 87.5% for hospitalization, 90.3% for ICU admission, and 86.3% for death.
8 Jul, 2021 | 09:22h | UTCEffectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile – New England Journal of Medicine
Related: Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years. AND WHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic. AND Brazilian town experiment shows mass vaccination can wipe out COVID-19.
Commentary on Twitter
Chile's data on Sinovac CoronaVac in NEJM: not controlled study. Model details pic 2
– doses 28 days apart (like Serrana trial)
– symptomatic disease 65.9% (65-67)
– hospitalization 87.5% (87-88)
– intensive care 90.3% (89-91)
– Covid death 86.3% (85-88)
https://t.co/CB1U8Ar163 pic.twitter.com/4HwASRCnwQ— Hilda Bastian, PhD (@hildabast) July 7, 2021
Mounting evidence suggests Sputnik COVID vaccine is safe and effective.
8 Jul, 2021 | 09:14h | UTCMounting evidence suggests Sputnik COVID vaccine is safe and effective – Nature
Antibiotic resistance during and beyond COVID-19.
8 Jul, 2021 | 09:09h | UTCAntibiotic resistance during and beyond COVID-19 – JAC-Antimicrobial Resistance
Schooling during COVID-19: Recommendations from the European Technical Advisory Group for schooling during COVID-19.
8 Jul, 2021 | 09:11h | UTC
COVID and schools: the evidence for reopening safely.
8 Jul, 2021 | 09:12h | UTCCOVID and schools: the evidence for reopening safely – Nature
ADA Draft Consensus Report: Management of Type 1 Diabetes in Adults.
8 Jul, 2021 | 09:04h | UTCThe Management of Type 1 Diabetes in Adults — A Consensus Report by the ADA and EASD
Commentaries: ADA/EASD Draft Guidance Aims to Bring Adults With Type 1 Diabetes Out of Shadows – Medscape (free registration required) AND New consensus report on adults with type 1 diabetes focuses on individualised care – Diabetes Times
Related: Guideline: ADA 2021 Standards of Medical Care in Diabetes
Perspective | Should People With Immune Problems Get Third Vaccine Doses?
8 Jul, 2021 | 09:07h | UTCShould People With Immune Problems Get Third Vaccine Doses? – The New York Times (a few articles per month are free)
Related: [Preprint] 3rd AstraZeneca shot gives strong immunity. AND Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.
Review: Non-invasive ventilatory support and high-flow nasal oxygen as first-line treatment of acute hypoxemic respiratory failure and ARDS.
8 Jul, 2021 | 09:01h | UTC
Commentary on Twitter
Physiology-to-bedside overview about non-invasive ventilatory support in AHRF & #ARDS
➡️spontaneous breathing: benefits/harms
➡️how to make spontaneous effort non‑injurious?
➡️optimizing HFNO & NIV
➡️monitoring to detect failure & be protective
➡️evidencehttps://t.co/KPW2u8akhA pic.twitter.com/yKVxrYaFmZ— Intens Care Med (@yourICM) July 7, 2021
Predictors of death and new disability after critical illness: a multicenter prospective cohort study.
8 Jul, 2021 | 08:59h | UTC
Commentary on Twitter
Predicting death & new disability after #ICU admission: only 41% of pts requiring > 24h of mechanical ventilation are alive/free of new disability at 6 months. Potentially impacting? age, illness severity, diagnosis. Results #FOAMcc https://t.co/bpto5JUumB
Here visual abstract ⬇️ pic.twitter.com/hRqybdNpLa— Intens Care Med (@yourICM) July 3, 2021
Review: Dietary recommendations for prevention of atherosclerosis.
8 Jul, 2021 | 09:03h | UTCDietary recommendations for prevention of atherosclerosis – Cardiovascular Research
News Release: What should I eat to avoid heart disease? – European Society of Cardiology
Commentary: Plant-Based Diet Best for Your Heart – HealthDay
Study Commentary: Febrile Neutropenia – Procalcitonin vs. MASCC Score.
8 Jul, 2021 | 08:57h | UTCFebrile Neutropenia – Procalcitonin vs MASCC Score – Journal Feed
Study Commentary: Decreased Antibiotic Use for Acute Otitis Media and Acute Sinusitis Following Implementation of Childhood PCV13 Immunization.
8 Jul, 2021 | 08:54h | UTC
Opinion | Time to assume that health research is fraudulent until proven otherwise?
8 Jul, 2021 | 08:58h | UTCTime to assume that health research is fraudulent until proven otherwise? – The BMJ Opinion
Related: How a Data Detective Exposed Suspicious Medical Trials
Commentary on Twitter
"It may be time to move from assuming that research has been honestly conducted and reported to assuming it to be untrustworthy until there is some evidence to the contrary."@Richard56 considers the scale of the problem of research fraudhttps://t.co/WQVbJyqw3o
— The BMJ (@bmj_latest) July 7, 2021
A narrative review of evidence to guide deprescribing among older adults.
8 Jul, 2021 | 08:51h | UTCRelated: Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens. (several resources on the subject)
M-A: Are antimicrobial stewardship interventions effective and safe in long-term care facilities?
8 Jul, 2021 | 08:52h | UTC
Systematic review: Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure.
8 Jul, 2021 | 08:48h | UTC
M-A: Continuation of antidepressants vs. sequential psychological interventions to prevent relapse in depression.
8 Jul, 2021 | 08:50h | UTCContinuation of Antidepressants vs Sequential Psychological Interventions to Prevent Relapse in Depression: An Individual Participant Data Meta-analysis – JAMA Psychiatry (link to abstract – $ for full-text)
Commentaries: Cognitive Therapy While Tapering Antidepressants May Be Alternative to Maintenance Medication – Psychiatric News Alert AND Psychotherapy Can Prevent Relapse When Discontinuing Antidepressants – Mad in America
Commentary on Twitter
Sequential delivery of a psychological intervention while tapering antidepressants may be a potential alternative to long-term medication use in recurrent #depression, regardless of clinical risk factors @JosefienUMH, @Claudib123 https://t.co/UURRmv6qQO
— JAMA Psychiatry (@JAMAPsych) May 19, 2021
Clinical guidelines for female lower urinary tract symptoms.
8 Jul, 2021 | 08:44h | UTCClinical Guidelines for Female Lower Urinary Tract Symptoms – International Journal of Urology
Guideline on the peri-operative management of patients with sickle cell disease.
8 Jul, 2021 | 08:46h | UTCGuideline on the peri-operative management of patients with sickle cell disease – Anaesthesia