Daily Archives: July 1, 2021
COVID-19 vaccines reduce severity, length, viral load for those who still get infected.
1 Jul, 2021 | 09:57h | UTCOriginal study: Prevention and Attenuation of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines – New England Journal of Medicine
Commentary on Twitter
The @CDCgov trial to rigorously assess mRNA vaccination suppression of covid infections as assessed with frequent NP swabs in nearly 4,000 participants
91% efficacy of blocking transmission of infection (2 doses); 40% reduction of viral load https://t.co/tI6LECbw42 pic.twitter.com/y85Vd9ih5A— Eric Topol (@EricTopol) June 30, 2021
RCT: Novavax vaccine conferred 89.7% protection against symptomatic SARS-CoV-2 infection and 100% protection against hospitalizations or deaths.
1 Jul, 2021 | 09:59h | UTCSafety and Efficacy of NVX-CoV2373 Covid-19 Vaccine – New England Journal of Medicine
Audio interview: Audio Interview: Another New Covid-19 Vaccine – New England Journal of Medicine
Related: Opinion | The mRNA vaccines are extraordinary, but Novavax is even better
Analysis: How long does covid-19 immunity last?
1 Jul, 2021 | 09:56h | UTCHow long does covid-19 immunity last? – The BMJ
The neurological manifestations of post-acute sequelae of SARS-CoV-2 infection.
1 Jul, 2021 | 09:55h | UTC
Systematic review: Border controls, restricted entry, quarantine essential for curbing COVID-19 and future pandemics.
1 Jul, 2021 | 09:53h | UTCNews release: Border controls, restricted entry, quarantine essential for curbing COVID-19 and future pandemics – British Medical Journal
Commentary: Strategies ID’d Than Can Interrupt Spread of Infectious Disease – HealthDay
RCT: Similar outcomes with 5 vs. 2 years of zoledronate treatment following adjuvant chemotherapy in early breast cancer.
1 Jul, 2021 | 09:50h | UTCOriginal Study: Prognosis of Patients With Early Breast Cancer Receiving 5 Years vs 2 Years of Adjuvant Bisphosphonate Treatment: A Phase 3 Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
1 Jul, 2021 | 09:44h | UTC
Commentary on Twitter
Now available in Annals of Oncology, the @myESMO clinical practice guidelines for the diagnosis, treatment and follow-up of anal cancer, a rare disease accounting for less than 1% of all cancers https://t.co/usnFsd00BJ pic.twitter.com/bI0v60j8Ft
— Annals of Oncology (@Annals_Oncology) June 30, 2021
AHA Scientific Statement: Evidence-based practices in the cardiac catheterization laboratory.
1 Jul, 2021 | 09:47h | UTC
Perspective | Why no one is sure if Delta is deadlier – “The variants are spreading faster, but they don’t necessarily have incentive to kill more often”.
1 Jul, 2021 | 09:52h | UTCWhy No One Is Sure If Delta Is Deadlier – The Atlantic
AHA Scientific Statement: Managing atrial fibrillation in patients with heart failure and reduced ejection fraction.
1 Jul, 2021 | 09:46h | UTCTop Things to Know: Managing Atrial Fibrillation in Patients With Heart Failure and Reduced Ejection Fraction
Commentary on Twitter
Pleased to share AHA Scientific statement on ‘Managing AF in pts with HFrEF’ just published @CirculationEP. https://t.co/WRx3QnrxHF Many thanks to the writing group and reviewers for making this excellent guidance document possible @AHAScience @American_Heart @CircAHA #Epeeps pic.twitter.com/PoqqlyA0iA
— Rakesh Gopinath (@drrakeshg1) June 23, 2021
M-A: Simultaneous use of hypertonic saline and IV furosemide for fluid overload – “Benefits of the HSS+Fx over Fx were observed across all examined outcomes in acute decompensated heart failure patients with fluid overload”.
1 Jul, 2021 | 09:41h | UTCSimultaneous Use of Hypertonic Saline and IV Furosemide for Fluid Overload: A Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text)
Systematic Review: Cilostazol for intermittent claudication – “Cilostazol has been shown to improve walking distance in people with intermittent claudication. However, participants taking cilostazol had higher odds of experiencing headache”.
1 Jul, 2021 | 09:42h | UTCCilostazol for intermittent claudication – Cochrane Library
Summary: Cilostazol for peripheral arterial disease – Cochrane Library