Daily Archives: March 3, 2021
NIH halts trial of COVID-19 convalescent plasma in emergency department patients with mild symptoms
3 Mar, 2021 | 08:55h | UTC
The vaccine race against the coronavirus variants, explained
3 Mar, 2021 | 08:52h | UTCThe vaccine race against the coronavirus variants, explained – Vox
WHO Guideline recommends against Hydroxychloroquine to prevent Covid-19
3 Mar, 2021 | 08:56h | UTCA living WHO guideline on drugs to prevent covid-19 – The BMJ
See also: WHO Living guideline: Drugs to prevent COVID-19 – World Health Organization
Commentaries: WHO advises against hydroxychloroquine to curb COVID-19 – CIDRAP AND WHO panel issues strong advice against hydroxychloroquine for COVID-19 – Reuters
Commentary on Twitter
The anti-inflammatory drug hydroxychloroquine should NOT be used to prevent infection in people who do not have #COVID19, according to the latest WHO clinical care guidance https://t.co/Oi2NJQMwiZ pic.twitter.com/0UQr78hNk4
— World Health Organization (WHO) (@WHO) March 2, 2021
COVID-19 research in critical care: the good, the bad, and the ugly
3 Mar, 2021 | 08:49h | UTCCOVID-19 research in critical care: the good, the bad, and the ugly – Intensive Care Medicine
Commentary on Twitter
Challenges, achievements, directions of critical care research in #pandemic, from early small #COVID19 studies (incomplete/inconsistent data), to large-scale registries, through overlapping/competing & underpowered trials, often with poor LMIC involvement.https://t.co/EyEui4pKPi pic.twitter.com/jUDXAVaD5z
— Intens Care Med (@yourICM) March 1, 2021
More transmissible and evasive SARS-CoV-2 variant growing rapidly in Brazil
3 Mar, 2021 | 08:53h | UTCOriginal study (preprint): Genomics and epidemiology of a novel SARS-CoV-2 lineage in Manaus, Brazil
Commentaries: Covid Brazil variant ‘may spread more easily’ – BBC AND Brazil coronavirus variant: what is it and why is it a concern? An expert explains – The Conversation
Covid-19: Single dose of Pfizer and Oxford vaccines cuts risk of hospital admission by 80% in over 80s, data suggest
3 Mar, 2021 | 08:51h | UTC
Commentary on Twitter
Both the Pfizer BioNTech and the Oxford AstraZeneca vaccines are highly effective in reducing covid-19 infections and protecting against severe disease in older adults, preliminary data show https://t.co/THSv5kiIVt
— The BMJ (@bmj_latest) March 2, 2021
A Practical Guide for Anesthesia Providers on the Management of COVID-19 Patients in the Acute Care Hospital
3 Mar, 2021 | 08:48h | UTC
How to make ‘immunity passports’ more ethical
3 Mar, 2021 | 08:46h | UTCHow to Make ‘Immunity Passports’ More Ethical – Scientific American
Related: Twelve criteria for the development and use of COVID-19 vaccine passports
USPSTF Draft Statement: Screening for Chlamydia and Gonorrhea in Sexually Active Women
3 Mar, 2021 | 08:43h | UTCScreening for Chlamydia and Gonorrhea – U.S. Preventive Services Task Force
Clinical application of serologic testing for COVID-19 in contemporary cardiovascular practice
3 Mar, 2021 | 08:44h | UTC
6 Steps to Better Imaging for Transgender Patients
3 Mar, 2021 | 08:39h | UTCSummary: 6 Steps to Better Imaging for Transgender Patients – Diagnostic Imaging
Original article: Imaging Health and Radiology Care of Transgender Patients: A Call to Build Evidence-Based Best Practices – Journal of the American College of Cardiology ($)
Commentary on Twitter
71% of transgender patients report having a negative imaging encounter. Researchers led by @UVMHealth offer 6 tips in @JACRJournal for improving imaging for this patient group. https://t.co/Ixha7tXF3v
— Diagnostic Imaging (@Dx_imaging) March 2, 2021
Role of advanced imaging in COVID-19 cardiovascular complications
3 Mar, 2021 | 08:45h | UTCRole of advanced imaging in COVID-19 cardiovascular complications – Insights into Imaging
ACOG Committee Opinion: Health care for transgender and gender diverse individuals
3 Mar, 2021 | 08:41h | UTCHealth Care for Transgender and Gender Diverse Individuals – Obstetrics & Gynecology
Using Bayesian Methods to Augment the Interpretation of Critical Care Trials. An Overview of Theory and Example Reanalysis of the Alveolar Recruitment for Acute Respiratory Distress Syndrome Trial
3 Mar, 2021 | 08:36h | UTC
Commentary on Twitter
I love this paper on Bayes.
Aren’t trials just like medical tests: they update our prior knowledge or beliefs?
If you can discuss a trial using its p-wave or confidence intervals, why not its posterior probabilities given *justified* priors.
(Yes, I am enthralled!) https://t.co/w1ym9jgQD5
— John Mandrola, MD (@drjohnm) March 1, 2021
The $450 question: Should journals pay peer reviewers?
3 Mar, 2021 | 08:33h | UTCThe $450 question: Should journals pay peer reviewers? – Science
Related: Richard Smith: Peer reviewers—time for mass rebellion? – The BMJ Opinion AND 5 Things We Learned About Peer Review in 2020 – Absolutely Maybe
RCT: High flow oxygen does not change the risk of mortality in patients with a suspected acute coronary syndrome
3 Mar, 2021 | 08:37h | UTC
Commentary on Twitter
Supplementary high flow oxygen given for ischaemic symptoms to patients with suspected acute coronary syndrome was not associated with a change in 30 day mortality, finds new #BMJResearchhttps://t.co/CDhfFyVL88
— The BMJ (@bmj_latest) March 2, 2021
Requests for brand name over generic prescription drugs cost the Medicare program $1.7 billion in a single year, study finds
3 Mar, 2021 | 08:31h | UTCOriginal study: Factors Associated With Prescriptions for Branded Medications in the Medicare Part D Program – JAMA Network Open
Commentary on Twitter
Economic evaluation finds prescribers & patients motivated 30% of branded drug dispensing in Medicare Part D, an incremental annual cost of $1.7 billion Medicare & $270 million to patients vs switching to generics. @dr_msocal @GeBaiDC @JohnsHopkinsSPH https://t.co/MkVJdzLczG
— JAMA Network Open (@JAMANetworkOpen) March 3, 2021
Expert consensus on practical aspects in the treatment of chronic urticaria
3 Mar, 2021 | 08:28h | UTC
M-A: Global burden of influenza-associated lower respiratory tract infections and hospitalizations among adults
3 Mar, 2021 | 08:30h | UTC
Review: Diagnostic challenges in chronic inflammatory demyelinating polyradiculoneuropathy
3 Mar, 2021 | 08:29h | UTCDiagnostic challenges in chronic inflammatory demyelinating polyradiculoneuropathy – Brain
M-A: Evaluation of exercise interventions and outcomes after hip arthroplasty
3 Mar, 2021 | 08:18h | UTC
Systematic review: Aldosterone antagonists for people with chronic kidney disease requiring dialysis
3 Mar, 2021 | 08:27h | UTCAldosterone antagonists for people with chronic kidney disease requiring dialysis – Cochrane Library
RCT: Effect of Blinatumomab vs. Chemotherapy in children with high-risk first-relapse B-Cell Acute Lymphoblastic Leukemia
3 Mar, 2021 | 08:19h | UTCEffect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)
Related study: Effect of Postreinduction Therapy Consolidation With Blinatumomab vs Chemotherapy on Disease-Free Survival in Children, Adolescents, and Young Adults With First Relapse of B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Blinatumomab for Treatment of Children With High-risk Relapsed B-Cell Acute Lymphoblastic Leukemia – JAMA (free for a limited period)
Chronic suppurative otitis media: Cochrane evidence on treatment options
3 Mar, 2021 | 08:26h | UTC
RCT: Omega-3 supplements do not reduce cardiovascular events in elderly patients after myocardial infarction
3 Mar, 2021 | 08:13h | UTCEffects of n-3 Fatty Acid Supplements in Elderly Patients After Myocardial Infarction: A Randomized, Controlled Trial – Circulation (link to abstract – $ for full-text)
Commentary: Omega-3 fatty acids did not reduce risk of cardiac events in elderly heart attack survivors – News Medical
Commentary on Twitter
OMEMI: In RCT of elderly patients with a recent acute myocardial infarction, n-3 fatty acid supplementation did not reduce clinical events. Read more: https://t.co/nGs5DGGtmT #AHAJournals @Oslounivsykehus @UniOslo @pmyhre @AAKalstad pic.twitter.com/I3Gr89ztyj
— Circulation (@CircAHA) February 11, 2021