Daily Archives: February 26, 2021
CDC studies on superspreading events at fitness facilities
26 Feb, 2021 | 08:44h | UTCCommentaries: Going maskless is a key factor in Covid-19 outbreaks at gyms, studies say – CNN AND A Chicago gym saw dozens of COVID-19 cases after infected people attended HIIT classes without masks – Insider
Conflicting results from 2 randomized trials testing Tocilizumab for Covid-19
26 Feb, 2021 | 08:48h | UTC
Commentary on Twitter
Why do 2 randomized trials of tocilizumab, an interleukin-6 blocker, for severe covid-19, have opposite results?
Today @NEJMhttps://t.co/g8LCrhhpLyhttps://t.co/BcN3wOwsl0 pic.twitter.com/sLrQUYI1pf— Eric Topol (@EricTopol) February 25, 2021
WHO Report: Preparing for Long COVID 2021
26 Feb, 2021 | 08:46h | UTCIn the wake of the pandemic: preparing for Long COVID (2021) – World Health Organization
Commentaries: Long COVID sufferer still has disease’s debilitating symptoms nearly a year after first falling ill – EuroNews AND Debilitating ‘long-COVID’ may have severe health, social impacts: WHO – Reuters
Related: Dr. Fauci says new data suggests ‘long’ Covid symptoms can last up to 9 months – CNBC
New protocol tested SARS-CoV-2 positivity on day 9 among quarantined student contacts of confirmed cases, resulting in safe reduction in loss of instructional time
26 Feb, 2021 | 08:42h | UTCCommentary: Is the CDC 10-day COVID-19 quarantine guideline enough? – News Medical
Commentary on Twitter
In this study of a 9-day testing protocol for student contacts of confirmed #COVID19 cases in 1 Florida county, a reduction in loss of instructional time was found that was less than what would have occurred with 14-day quarantine https://t.co/YPft2oAvYk
— JAMA (@JAMA_current) February 19, 2021
Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19
26 Feb, 2021 | 08:43h | UTCCommentary: Studies help discern severe COVID from related kids’ syndrome – CIDRAP
Commentary on Twitter
In this case series using national MIS-C registry data, kids w MIS-C were younger (6-12 y), more likely to be non-Hispanic Black, & have severe CV or mucocutaneous involvement and more extreme inflammation vs kids w severe #COVID19 https://t.co/jmCCDPXLmf @BostonChildrens
— JAMA (@JAMA_current) February 25, 2021
Study finds increased COVID-19 mortality among adults with Down syndrome
26 Feb, 2021 | 08:39h | UTCCommentaries: Adults with Down syndrome 3 times more likely to die of COVID, study finds – CIDRAP AND International study finds increased COVID-19 mortality among adults with Down syndrome – Case Western Reserve University
Related: COVID-19 is 10 times deadlier for people with Down syndrome, raising calls for early vaccination – Science (a few articles per month are free)
COVID-19 hospitalizations attributable to cardiometabolic conditions
26 Feb, 2021 | 08:40h | UTCCommentary: Study estimates two-thirds of COVID-19 hospitalizations due to four conditions – Tufts University
Commentary on Twitter
Our new research suggests 63% of US hospitalizations for COVID may have been prevented, due to less severe illness, if we had a metabolically healthy population. Biggest risk: obesity, responsible for 30% of excess hospitalizations. https://t.co/no8YhACf4E pic.twitter.com/4VPuHT0OPd
— Dariush Mozaffarian (@Dmozaffarian) February 25, 2021
Opinion – Catching COVID from surfaces is very unlikely. So perhaps we can ease up on the disinfecting
26 Feb, 2021 | 08:38h | UTCRelated: Coronavirus is in the air — there’s too much focus on surfaces – Nature AND COVID-19 rarely spreads through surfaces. So why are we still deep cleaning? – Nature
Cohort study: A single conventional Troponin combined with HEART score may be as good as serial measurements for safe discharge of patients with chest pain in the ED
26 Feb, 2021 | 08:32h | UTCEditorial: Troponin Testing in the Emergency Department—When 2 Become 1
Commentary: Single Troponin Test May Be Enough for Safe Discharge of Chest Pain Patients – TCTMD
RCT: Effect of screening by clinical breast examination on breast cancer incidence and mortality after 20 years
26 Feb, 2021 | 08:34h | UTCCommentaries: The story of the Mumbai breast screening study – The BMJ Opinion
This trial found that regular breast examination by trained female health workers in Mumbai led to earlier diagnosis and reduced deaths from breast cancer in women aged 50 and olderhttps://t.co/TQCHLbVO8L
— The BMJ (@bmj_latest) February 25, 2021
CAR T-cell therapy produces deep, sustained remissions in patients with relapsed myeloma
26 Feb, 2021 | 08:31h | UTCOriginal study: Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma – New England Journal of Medicine
Editorial: Five principles for the intelligent use of AI in medical imaging
26 Feb, 2021 | 08:29h | UTCFive principles for the intelligent use of AI in medical imaging – Intensive Care Medicine
Commentary on Twitter
5 key principles that should be remembered for smart use of #ArtificialIntelligence as adoption of #MachineLearning systems becomes more widespread in medical imaging:
➡️knowledge base
➡️metrics
➡️bias
➡️model fragility
➡️error-prone behavior#DataScience https://t.co/h1iFAyCq35 pic.twitter.com/OvNVtwfl94— Intens Care Med (@yourICM) January 17, 2021
Integrated palliative and oncology care for patients receiving treatment for acute myeloid leukemia
26 Feb, 2021 | 08:25h | UTCOriginal article: Effectiveness of Integrated Palliative and Oncology Care for Patients With Acute Myeloid Leukemia: A Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)
Decreasing patient-reported burden of treatment: A systematic review of quantitative interventional studies
26 Feb, 2021 | 08:21h | UTC
Phase 2 trial: Muscarinic cholinergic receptor agonist and peripheral antagonist for schizophrenia
26 Feb, 2021 | 08:30h | UTCMuscarinic Cholinergic Receptor Agonist and Peripheral Antagonist for Schizophrenia – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Phase II Results Promising for New Schizophrenia Drug Combo – MedPage Today
Systematic Review: Insufficient evidence to decide whether surgical intervention is beneficial or harmful for the early management of Bell’s palsy
26 Feb, 2021 | 08:20h | UTCSurgical interventions for the early management of Bell’s palsy – Cochrane Library
Summary: Surgical operation for Bell’s palsy (idiopathic facial paralysis) – Cochrane Library
Myocarditis and inflammatory cardiomyopathy: current evidence and future directions
26 Feb, 2021 | 08:18h | UTCMyocarditis and inflammatory cardiomyopathy: current evidence and future directions – Nature Reviews Cardiology (free for a limited period)
Drains, germs, or steel: Multidisciplinary management of acute colonic diverticulitis
26 Feb, 2021 | 08:17h | UTC
Randomized trial: Oral Azacitidine maintenance therapy for acute myeloid leukemia in first remission
26 Feb, 2021 | 08:23h | UTCOral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Maintenance Oral Azacitidine for Patients With AML in First Remission: QUAZAR AML-001 Trial – The ASCO Post
Study: Unhealthy alcohol use common after bariatric surgery
26 Feb, 2021 | 08:14h | UTCCommentaries: Unhealthy Alcohol Use—A Common Iatrogenic Complication of Bariatric Surgery – JAMA Network Open AND Bariatric Surgery May Increase Risk of Unhealthy Alcohol Use – Psychiatric News Alert AND Bariatric Surgery Ups Risk of Alcohol Abuse – Physician’s Weekly
Commentary on Twitter
Our team’s analysis of VA bariatric surgery outcomes. Alcohol use increased 3–8 years after surgery. The benefits far outweigh the risks, but we need to support our patients long-term. @davearterburn @NeilFlochMD https://t.co/QpGHeRrI9l via @JAMANetworkOpen part of @JAMANetwork
— Luke Funk, MD, MPH (@lmfunk2) December 26, 2020
Guidelines for the treatment of irritable bowel syndrome
26 Feb, 2021 | 08:15h | UTC
RCT: Dimenhydrinate and metoclopramide equally effective in the treatment of nausea due to vertigo
26 Feb, 2021 | 08:12h | UTCComparison of efficacy dimenhydrinate and metoclopramide in the treatment of nausea due to vertigo; a randomized study – The American Journal of Emergency Medicine (link to abstract – $ for full-text)