Daily Archives: January 27, 2021
Low-dose aspirin may improve pregnancy chances for women with one or two prior miscarriages
27 Jan, 2021 | 01:09h | UTCOriginal study: The Effect of Preconception-Initiated Low-Dose Aspirin on Human Chorionic Gonadotropin–Detected Pregnancy, Pregnancy Loss, and Live Birth: Per Protocol Analysis of a Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Summary for Patients: The Effect of Preconception-Initiated Low-Dose Aspirin on Human Chorionic Gonadotropin–Detected Pregnancy, Pregnancy Loss, and Live Birth – Annals of Internal Medicine
Related (study and commentaries): Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled trial – The Lancet
AHA Statement: Psychological health, well-being, and the mind-heart-body connection
27 Jan, 2021 | 01:11h | UTCNews release: Mental health is important to overall health, and heart disease prevention and treatment – American Heart Association
Commentary: The head is connected to the heart – and can influence health – American Heart Association
Meta-analysis: Minimally invasive surgery versus transcatheter aortic valve replacement
27 Jan, 2021 | 01:00h | UTCCommentary: TAVI vs Minimally Invasive AVR Yields Surprising Findings: Meta-analysis – TCTMD
Commentary on Twitter
Comprehensive systematic review and meta-analysis of miniAVR vs #TAVR. Important in the context of 'lifetime management of valves'. Thank you for the opportunity. @Shoukmed @ahmedsayed8991 @BrighamSurgery @BrighamThoracic CC:@TSRA_official @STS_CTsurgery @AATSED @ThoracicsCanada https://t.co/T1XDrebl8U pic.twitter.com/5E5eOLherA
— Sameer Hirji (@Hirji1987) January 21, 2021
Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases
27 Jan, 2021 | 01:08h | UTCVitamin D, Calcium, Other Vitamins, and Supplements Do Not Prevent CVD – TCTMD
Original study 1: Vitamin D, Calcium Supplements, and Implications for Cardiovascular Health: JACC Focus Seminar – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Original study 2: Vitamin D, Calcium Supplements, and Implications for Cardiovascular Health: JACC Focus Seminar – Journal of the American College of Cardiology (link to abstract – $ for full-text)
RCT: In a population with a high prevalence of Rheumatic Heart Disease, screening schoolchildren with echocardiography can enable timely initiation of secondary antibiotic prophylaxis
27 Jan, 2021 | 01:05h | UTCCommentaries: Echo Screening for Rheumatic Heart Disease in Kids Gets a Boost – TCTMD
Editorial: Screening for Rheumatic Heart Disease—Quo Vadis?
Author interview: Systematic Echocardiographic Screening for Rheumatic Heart Disease in Nepalese Schoolchildren – JAMA
Commentary on Twitter
RHD accounts for the highest number of deaths due to #VHD worldwide. Cluster RCT in Nepal indicates effectiveness of early detection of clinically silent #RHD by echocardiographic screening of schoolchildren and timely initiation of secondary prophylaxis https://t.co/gCCt4LzV7X
— JAMA Cardiology (@JAMACardio) January 20, 2021
It took us 9 years to complete this cluster randomized clinical trial; for me this meant two children, a Colombian family, Spanish, moving home three times, nine trips to Nepal, public health @LSHTM, and from #Kilimanjaro to #ChoOyu. https://t.co/uMs4ZQzCYX pic.twitter.com/ZFBAlwEZDd
— Thomas Pilgrim (@ThomPilgrim) January 20, 2021
DEVT, SKIP Trials Add Support for Omitting IV tPA Before Stroke Thrombectomy
27 Jan, 2021 | 01:01h | UTCDEVT, SKIP Trials Add Support for Omitting IV tPA Before Stroke Thrombectomy – TCTMD
Original studies and commentaries: Randomized trial: Endovascular treatment alone noninferior to intravenous alteplase plus endovascular treatment on functional independence in patients with acute ischemic stroke
CDC: One in five people in U.S. has a sexually transmitted infection
27 Jan, 2021 | 00:58h | UTCCDC: One in five people in U.S. has a sexually transmitted infection – UPI
Original study: Sexually Transmitted Infections Among US Women and Men: Prevalence and Incidence Estimates, 2018 – Sexually Transmitted Diseases
Position Paper: Composition, structure, and function of heart teams
27 Jan, 2021 | 00:57h | UTC
Meta-analysis of observational studies: Fried-food consumption linked to increased risk of cardiovascular disease and all-cause mortality
27 Jan, 2021 | 00:55h | UTCCommentaries: Fried food intake linked to heightened serious heart disease and stroke risk – The BMJ AND Expert reaction to study looking at fried food and heart disease and stroke risk – Science Media Centre
Systematic review: Payment methods for healthcare providers working in outpatient healthcare settings
27 Jan, 2021 | 00:56h | UTCSummary: Payment methods for healthcare providers in outpatient healthcare settings – Cochrane Library
Commentary on Twitter
Payment methods for #healthcare providers in #outpatient healthcare settings https://t.co/wY6LKEmhbZ New @CochraneEPOC systematic review w evidence from 27 studies suggests that different payment methods can affect healthcare provider behaviour in both positive and negative ways.
— Cochrane (@cochranecollab) January 21, 2021
CDC Report: Low risk of COVID-19 transmission in schools with precautions in place
27 Jan, 2021 | 01:25h | UTCRelated viewpoint: Data and Policy to Guide Opening Schools Safely to Limit the Spread of SARS-CoV-2 Infection – JAMA
Commentary on Twitter
Important study:
While covid test + rates ranged from 7 to 40% in the community, K-12 schools were able to open with nearly no transmission linked to school.The harm of school closure will tear the fabric of society; these steps are worth it to reopen. https://t.co/q0SXpqJrqw pic.twitter.com/rsL7EkVsZZ
— Dr. Vinay Prasad MD MPH, Associate Professor (@VPrasadMDMPH) January 26, 2021
Editorial: The world needs a single naming system for coronavirus variants (geographic associations risk stigma)
27 Jan, 2021 | 01:24h | UTCThe world needs a single naming system for coronavirus variants – Nature
Opinion: Monoclonal antibodies yet to show important clinical benefit in patients with Covid-19
27 Jan, 2021 | 01:23h | UTCSee also: PulmCrit Wee – Follow-up Bamlanivimab study unmasks statistical chicanery
[Press release – not published yet] Neutralizing antibodies bamlanivimab and etesevimab together reduced risk of COVID-19 hospitalizations and death by 70 percent
27 Jan, 2021 | 01:22h | UTCCommentary: Lilly antibody combo therapy cuts risk of COVID-19 deaths – Reuters
Commentary on Twitter
1st Phase 3 trial results on #SARSCoV2 monoclonal antibody combination with very positive results
1035 patients: 11 (2%) v (7%) for death or hospitalization and 0 vs 10 deaths in high-risk patients, given early https://t.co/BXnwCd64O9 (press release).
Coincides w/ EUA criteria. pic.twitter.com/3MjE0XtEqF— Eric Topol (@EricTopol) January 26, 2021
WHO Updated Guideline: COVID-19 clinical management
27 Jan, 2021 | 01:26h | UTCCOVID-19 Clinical management: living guidance – World Health Organization
News release: WHO recommends follow-up care, low-dose anticoagulants for COVID-19 patients
Commentary: WHO issues new clinical advice on treating COVID-19 patients – Reuters
[Press release – not published yet] REGENERON reports positive interim data with antibody cocktail used as passive vaccine to prevent COVID-19
27 Jan, 2021 | 01:21h | UTCCommentaries: Regeneron’s antibody cocktail effective in preventing COVID-19 infection: study – Reuters AND Regeneron says monoclonal antibodies prevent Covid-19 in study – STAT AND Expert reaction to press release from Regeneron giving interim data from its REGEN-COV™ antibody cocktail trial for the prevention of COVID-19 in people at high risk of infection – Science Media Centre
Systematic review: Cardiopulmonary resuscitation in the prone position in the operating room or in the intensive care unit
27 Jan, 2021 | 01:14h | UTC
Commentary on Twitter (thread – click for more)
? Though the prone position is used in the OR for certain procedures and in the ICU to optimize oxygenation, prone CPR is also successful, though speed to recognize and initiate chest compressions while in the prone position is important. https://t.co/bpA9FfpfuC pic.twitter.com/JntkmQdapJ
— Anesthesia&Analgesia (@IARS_Journals) January 17, 2021
Early warnings of COVID-19 outbreaks across Europe from social media
27 Jan, 2021 | 01:17h | UTCEarly warnings of COVID-19 outbreaks across Europe from social media – Scientific Reports
Commentary on Twitter
Where do you go to find the 1st, earliest signs of covid-19 in Europe?@Twitter https://t.co/H5SuMpiR6K @SciReports @IMTLucca
Incorporate social media into digital surveillance efforts pic.twitter.com/SjcpZXlYTs— Eric Topol (@EricTopol) January 25, 2021
Israel sees 60% drop in hospitalizations for age 60-plus 3 weeks after 1st shot
27 Jan, 2021 | 01:19h | UTCRelated: No serious COVID-19 cases among Israelis given Pfizer shot, minister says – Reuters
In a major setback, Merck to stop developing its two Covid-19 vaccines and focus on therapies
27 Jan, 2021 | 01:18h | UTCIn a major setback, Merck to stop developing its two Covid-19 vaccines and focus on therapies – STAT