Daily Archives: November 11, 2020
Opinion: “Why the Pfizer and BioNTech vaccine is a cause for optimism — and skepticism. Vaccine science by press release has to stop”
11 Nov, 2020 | 09:25h | UTCWhy the Pfizer and BioNTech vaccine is a cause for optimism — and skepticism – Vox
Related commentaries: Champagne and questions greet first data showing that a COVID-19 vaccine works – Science AND 90% efficacy for Pfizer’s COVID-19 mRNA vaccine is striking. But we need to wait for the full data – The Conversation
See also: Science by press release: When the story gets ahead of the science – CNN
Pfizer vaccine: What an ‘efficacy rate above 90%’ really means
11 Nov, 2020 | 09:23h | UTCPfizer vaccine: what an ‘efficacy rate above 90%’ really means – The Conversation
Pfizer’s ultra-cold vaccine could be difficult to distribute
11 Nov, 2020 | 09:22h | UTCPfizer’s ultra-cold vaccine could be difficult to distribute – The Conversation
Covid-19: Reopening places such as restaurants, gyms, hotels, cafes, and religious organizations are predicted to cause the largest increase in infections
11 Nov, 2020 | 09:26h | UTCMobility network models of COVID-19 explain inequities and inform reopening – Nature
Commentaries: Restaurants and gyms were spring ‘superspreader’ sites. Occupancy limits could control Covid, new study predicts – STAT AND How to stop restaurants from driving COVID infections – Nature AND Covid Superspreader Risk Is Linked to Restaurants, Gyms, Hotels – Bloomberg AND Covid-19 modeling study suggests which places may have highest risk of spread — but occupancy limits can help – CNN
Commentary on Twitter
Reopening places such as restaurants, fitness centers, cafes, and hotels carries the highest risk for transmitting SARS-CoV-2, according to a study in Nature. Reducing occupancy in these venues may result in a large reduction in predicted infections. https://t.co/aSSrwnnep9 pic.twitter.com/GdTZdZy12Y
— Nature (@nature) November 10, 2020
Randomized trial: vitamin D, omega-3 fatty acids, or a strength-training exercise program do not improve clinical outcomes in older adults
11 Nov, 2020 | 09:11h | UTCEffect of Vitamin D Supplementation, Omega-3 Fatty Acid Supplementation, or a Strength-Training Exercise Program on Clinical Outcomes in Older Adults: The DO-HEALTH Randomized Clinical Trial – JAMA (free for a limited period)
Study: N95 masks with exhalation valves do not work
11 Nov, 2020 | 09:20h | UTCCommentary: N95 Masks With Exhalation Valves Don’t Slow The Spread Of Covid-19 – Forbes
Commentary on Twitter
N95 ??with valves don't workhttps://t.co/qGZIEzE1Sh @AIP_Publishing today pic.twitter.com/mI9pVmFtfa
— Eric Topol (@EricTopol) November 10, 2020
Derivation and validation of the HA2T2 (Hypoxia, Age, Troponin) COVID‐19 mortality risk score
11 Nov, 2020 | 09:18h | UTC
Commentary on Twitter
Predicting in-hospital mortality among patients with #COVID19 using the simple HA2T2 (hypoxia, age and troponin) score. https://t.co/FTDceIijZl @KevinManocha @bradpeltzer @MonikaSafford @ParagGoyalMD @JAHA_AHA @WeillCornell @nyphospital pic.twitter.com/vGTNSg8wyO
— Jim Cheung (@DrJCheungEP) November 10, 2020
[Not Published Yet] Randomized trial: Long-acting injectable drug every 8 weeks is highly effective in preventing HIV acquisition in women
11 Nov, 2020 | 09:17h | UTCCommentary: NIH study finds long-acting injectable drug prevents HIV acquisition in cisgender women – NIH News Releases
USPSTF Statement: Insufficient evidence to recommend screening for high blood pressure in children and adolescents
11 Nov, 2020 | 09:14h | UTCScreening for High Blood Pressure in Children and Adolescents – U.S. Preventive Services Task Force
Author interview: USPSTF Recommendation: Screening for Hypertension in Children and Adolescents
JAMA Patient Page: Screening for High Blood Pressure in Children and Adolescents
[Abstract Only] Randomized trial: Intravenous haloperidol more effective than ondansetron for cannabis hyperemesis syndrome
11 Nov, 2020 | 09:08h | UTC
Commentary on Twitter
Excited to have been involved in this practice-changing RCT comparing Haloperidol (superior) to Ondansetron for Cannabis Hyperemesis Syndrome from @Qemerg @therealdraa_ron @savforrester Marco Sivilotti and others! Check it out!https://t.co/ylms5JIO9v
— Andrew Koch Hall (@AKHallMD) November 5, 2020
KDIGO Guideline Synopsis: Diabetes management in chronic kidney disease. Use of ACE inhibitors or ARBs, glycemic monitoring and targets, and choice of antihyperglycemic drugs are covered
11 Nov, 2020 | 09:09h | UTCOriginal guideline: Kidney Disease: Improving Global Outcomes (KDIGO) 2020 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease
Podcast on chronic cough. Don’t be afraid to try empiric therapies! PPIs for GERD, antihistamines and intranasal steroids for post-nasal drip, and inhaled corticosteroids for post-viral cough are generally low-risk and will treat many cases.
11 Nov, 2020 | 09:04h | UTC#241 Chronic Cough – The Curbsiders Internal Medicine Podcast
Meta-analysis: Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging can reduce cases of severe disability but increases symptomatic intracranial hemorrhage and deaths
11 Nov, 2020 | 09:06h | UTCIntravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data – The Lancet (free registration required)
Commentary on Twitter
Latebreaking at #ESOWSO2020—Intravenous alteplase for #stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data https://t.co/KDX2lHisbj pic.twitter.com/cnoiRhIReF
— The Lancet (@TheLancet) November 8, 2020