Daily Archives: September 6, 2020
Coalition Covid-19 Brazil – Randomized trial: Azithromycin not beneficial for patients admitted to the hospital with severe Covid-19
6 Sep, 2020 | 22:06h | UTCInvited Commentary: Azithromycin for severe COVID-19
Commentaries on Twitter
This network of Brazilian researchers has done an AMAZING job of getting organized & answering important ?s. In this Lancet article they show in a randomized trial that #azithromycin does not improve #Covid19 outcomes. @RenatoDLopes1 https://t.co/zL7GSaVqm8
— C. Michael Gibson MD (@CMichaelGibson) September 5, 2020
New trial @TheLancet does not support the routine use of azithromycin in combination with #Hydroxychloroquine in patients with severe #COVIDー19:https://t.co/vaj1XX3dSo
— Madhu Pai (@paimadhu) September 6, 2020
We have heard your message about long covid and we will act, says WHO
6 Sep, 2020 | 21:59h | UTCWe have heard your message about long covid and we will act, says WHO – The BMJ Opinion
Commentary on Twitter
I joined an inspiring meeting with #COVID19 patient groups. My colleague @mvankerkhove contacted these great advocates who strive to increase research, rehabilitation and recognition for people suffering long-term effects of the virus. @WHO is committed to supporting their goals. https://t.co/wJpYupcLjQ
— Tedros Adhanom Ghebreyesus (@DrTedros) August 22, 2020
A living WHO guideline on drugs for Covid-19
6 Sep, 2020 | 22:04h | UTCA living WHO guideline on drugs for covid-19 – The BMJ
Commentary on Twitter
NEW #RapidRec makes a strong recommendation for systemic corticosteroids in patients with severe and critical #COVID19 and a weak or conditional recommendation against systemic corticosteroids in patients with non-severe covid-19 https://t.co/p7loBk95Vm
— The BMJ (@bmj_latest) September 5, 2020
Post-COVID syndrome severely damages children’s hearts; ‘immense inflammation’ causing cardiac blood vessel dilation
6 Sep, 2020 | 22:03h | UTCOriginal Study: Multisystem inflammatory syndrome in children: A systematic review – EClinicalMedicine
Commentary on Twitter
#COVID19 Multisystem inflammatory syndrome in children: A systematic review
An abnormal echocardiograph was observed in 314 of 581 patients (54·0%) with depressed ejection fraction (45·1%, n = 262 of 581) comprising the most common aberrancy.https://t.co/JqgETbH3DL pic.twitter.com/GqYtvGy0oP
— EPIDATUM (@epidatum) September 5, 2020
Video: Long covid: diagnosis, management, prognosis
6 Sep, 2020 | 21:58h | UTCLong covid: diagnosis, management, prognosis – The BMJ
Commentary on Twitter
#LongCovid #BMJcovid – Many patients who have relatively mild symptoms from covid-19, continue to experience these long after the usual 12 day duration.
Our panel discusses "Long covid" – it's diagnosis, management and prognosis https://t.co/hsP1TRNCt3 via @YouTube
— The BMJ (@bmj_latest) September 5, 2020
Coronavirus reinfections: Three questions scientists are asking
6 Sep, 2020 | 21:56h | UTCCoronavirus reinfections: three questions scientists are asking – Nature
Does the COVID-19 cytokine storm exist?
6 Sep, 2020 | 21:55h | UTCDoes the COVID-19 cytokine storm exist? – Radboud University Medical Center
Original Study: Cytokine Levels in Critically Ill Patients With COVID-19 and Other Conditions – JAMA
Commentary on Twitter
Study suggests #COVID19 may not be characterized by cytokine storm. Whether anticytokine therapies will benefit patients with COVID-19 remains to be determined https://t.co/alyFUwCYRC
— JAMA (@JAMA_current) September 4, 2020
Infographic. Clinical recommendations for return to play during the COVID-19 pandemic
6 Sep, 2020 | 21:54h | UTC
Commentary on Twitter
Took a while for this to be out but excited 2 see our paper made it to infographic @BJSM_BMJ Clinical recommendations for return to play during the COVID-19 pandemichttps://t.co/rS3bCeP4Qg
Huge Collective Viewpoint by @SportswiseUK @aaashafik @GrahamHolloway4 @merseysportsmed pic.twitter.com/icYjY4D1e1— Dora Papadopoulou ? ???????????? (@Dora_Sportmed) September 4, 2020
COVID-19 in healthcare workers: A living systematic review and meta-analysis of prevalence, risk factors, clinical characteristics, and outcomes
6 Sep, 2020 | 21:49h | UTC
Commentary on Twitter
The figure summarizes the main findings of our meta-analysis published yesterday at the American Journal of Epidemiology.
Health care workers suffer a significant burden
from #COVID19 https://t.co/ymI56TRbm1
@SergioA18489499 @ISPMBern @OscarH_Franco @diromiza pic.twitter.com/NCaqD0xOET— Taulant Muka, MD, MPH, PhD (@muka_taulant) September 2, 2020
A direct comparison of enhanced saliva to nasopharyngeal swab for the detection of SARS-CoV-2 in symptomatic patients
6 Sep, 2020 | 21:51h | UTC
Practical Guide: Cardiorespiratory considerations for return-to-play in elite athletes after COVID-19 infection
6 Sep, 2020 | 21:52h | UTC
Commentary on Twitter
With #COVID-19 likely to be with us for a while, maybe this is one to pin on the clinic wall…
Top quality practical recommendations for the SEM doc – by some big hitters – @Breathe_to_win @SSharmacardio @Prof_MatWilson & team #LoveAFlowCharthttps://t.co/hNfx15W5h3 pic.twitter.com/t03zBVUcc2
— BJSM (@BJSM_BMJ) September 4, 2020
Phase 1–2 trial of a SARS-CoV-2 recombinant spike protein nanoparticle vaccine
6 Sep, 2020 | 21:44h | UTC
Immunological considerations for COVID-19 vaccine strategies
6 Sep, 2020 | 21:47h | UTCImmunological considerations for COVID-19 vaccine strategies – Nature Reviews Immunology
Commentary on Twitter
NEW #Review: 'Immunological considerations for COVID-19 vaccine strategies'
All you need to know about the #Covid19 vaccines in preclinical and clinical developmenthttps://t.co/AImMP6fLr0
FREE to access@MacImmunology pic.twitter.com/J1ycBsgJ3c— Nature Rev Immunol (@NatRevImmunol) September 5, 2020
Russian coronavirus vaccine results have been published
6 Sep, 2020 | 21:48h | UTCCommentaries: COVID-19 vaccines: early success and remaining challenges – The Lancet AND The Russian vaccine for COVID-19 – The Lancet Respiratory Medicine AND Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine – News Medical / The Lancet AND Russian coronavirus vaccine results have been published – here’s what they reveal – The Conversation
Commentary on Twitter
NEW—Preliminary results from Russian trials find that #COVID19 vaccine candidates led to no serious adverse events and elicit antibody response https://t.co/jGUwQa8oNd
Thread (1/8) pic.twitter.com/NWBpWDvUK3
— The Lancet (@TheLancet) September 4, 2020
Attitudes toward a potential SARS-CoV-2 vaccine: A survey of U.S. adults
6 Sep, 2020 | 21:45h | UTC
Chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19: An evidence-based clinical practice guideline
6 Sep, 2020 | 21:43h | UTC
Invasive Fungal Disease complicating COVID-19: when it rains it pours
6 Sep, 2020 | 21:38h | UTCInvasive Fungal Disease complicating COVID-19: when it rains it pours – Clinical Infectious Diseases
Related study: A national strategy to diagnose COVID-19 associated invasive fungal disease in the ICU – Clinical Infectious Diseases
Commentary on Twitter
Read the fantastic editorial commentary by @martinhoenigl
Invasive Fungal Disease complicating COVID-19: when it rains it pours. #COVID19 @eurconfmedmycol #CID https://t.co/3M7NYI3zwk https://t.co/2YKpQ3x9TP— Antibiotic Steward? Bassam Ghanem (@ABsteward) September 5, 2020
ESMO Expert Consensus: Managing cancer patients during the COVID-19 pandemic
6 Sep, 2020 | 21:40h | UTC
Cohort study: COVID-19 prevalence and mortality in patients with cancer and the effect of primary tumor subtype and patient demographics
6 Sep, 2020 | 21:42h | UTCCommentaries: New study describes which cancer patients are more vulnerable to COVID-19 – University of Birmingham AND COVID-19 Prevalence and Mortality in Patients With Cancer in the UK – The ASCO Post
#ESCCongress – [Not Published Yet] Trial clarifies which patients with acute pulmonary embolism can be managed at home
6 Sep, 2020 | 21:36h | UTCNews Release: Trial clarifies which patients with acute pulmonary embolism can be managed at home – European Society of Cardiology
HESTIA Calculator: Hestia Criteria for Outpatient Pulmonary Embolism Treatment – MdCalc
sPESI Calculator: Simplified PESI (Pulmonary Embolism Severity Index) – MeCalc
Systematic review: Association between D-Dimer levels and mortality in patients with COVID-19
6 Sep, 2020 | 21:37h | UTC
Randomized trial: Negative-pressure wound therapy compared with standard dressings following surgical treatment of major trauma to the lower limb
6 Sep, 2020 | 21:33h | UTCSource: EvidenceAlerts
Commentaries on Twitter
Should we use “Negative Pressure Dressings” in high risk major trauma wounds?
Paper early 2020 in JAMA https://t.co/I3SZfy62K1
Blow-by-blow account today (all 114 pages!) https://t.co/V6UbWItCmN
Spoiler: No – no difference@BritOrthopaedic @OrthoFolks @bota_uk @JAMA_current pic.twitter.com/PUQoCwz4Zr
— Dan Perry (@MrDanPerry) August 24, 2020
New NIHR-funded research finds standard dressings better than negative-pressure wound therapy for patients having #surgery for major leg #trauma: https://t.co/npGSNhz4XE#NIHRJL#openaccess pic.twitter.com/GSsGtyjla6
— NIHR Evidence (@NIHRevidence) August 26, 2020
[Abstract Only] Randomized trial: Aspirin increases major GI bleeding risk by 60% in older individuals
6 Sep, 2020 | 21:30h | UTCSource: EvidenceAlerts
Commentary on Twitter
Aspirin increases GI bleeding risk by 60% in an aspirin RCT
137 total GI bleeds in 90000 person years @Gut_BMJ https://t.co/Hb8h6kZrpo
— Elliot Tapper (@ebtapper) August 8, 2020
Randomized placebo-surgery controlled trial evaluates arthroscopic partial meniscectomy for a degenerative meniscus tear: a 5 year follow-up
6 Sep, 2020 | 21:34h | UTC
Commentary on Twitter
HOT OFF THE PRESS***
5 year follow-up results of the FIDELITY trial (arthroscopic partial meniscectomy VS placebo surgery for degenerative meniscal tears)
Another crushing blow for the #SexyScalpel? #OpenAccess by @anttimal @shamteppo & co!https://t.co/furVdovR9v pic.twitter.com/2gwNsQTk0s
— BJSM (@BJSM_BMJ) August 29, 2020
Meta-analysis (randomized trials + cohort studies) suggests improved outcomes with early norepinephrine for septic shock
6 Sep, 2020 | 21:27h | UTCEarly Norepinephrine for Septic Shock – JournalFeed
Original Study: Timing of norepinephrine initiation in patients with septic shock: a systematic review and meta-analysis – Critical Care
“Further randomized clinical studies should be conducted in order to confirm the results.” (from Critical Care)