Daily Archives: January 19, 2020
WHO Report: Lack of New Antibiotics Threatens Global Efforts to Contain Drug-resistant Infections
19 Jan, 2020 | 21:46h | UTCSee Reports: Antibacterial agents in clinical development – an analysis of the antibacterial clinical development pipeline – World Health Organization (free PDF) AND Antibacterial agents in preclinical development – World Health Organization (free PDF)
Commentary: W.H.O. Warns That Pipeline for New Antibiotics Is Running Dry – The New York Times (10 articles per month are free)
AGA Clinical Practice Guidelines on the Management of Moderate to Severe Ulcerative Colitis
19 Jan, 2020 | 21:47h | UTCRelated: British Society of Gastroenterology Guidelines on the Management of Inflammatory Bowel Disease (guidelines on the subject)
ESC Position Paper: Peripartum Management of Hypertension
19 Jan, 2020 | 21:51h | UTC
The PEPTIC Randomized Clinical Trial: Similar Outcomes with Stress Ulcer Prophylaxis with Proton Pump Inhibitors vs. Histamine-2 Receptor Blockers Among ICU Patients Receiving Invasive Mechanical Ventilation
19 Jan, 2020 | 21:42h | UTCEditorial: Proton Pump Inhibitors vs Histamine-2 Receptor Blockers for Stress Ulcer Prophylaxis in Critically Ill Patients: Issues of Interpretability in Pragmatic Trials (free for a limited period)
Conference Presentation: Effect of Stress Ulcer Prophylaxis With PPIs vs H2RBs on Mortality in Ventilated ICU Patients (free)
Commentaries: JC: The PEPTIC study PPI vs H2RBs on the ICU – St Emlyn’s (free) AND Risks And Benefits Of Proton Pump Inhibitors To Prevent Gi Bleeds In Intensive Care Patients – MedicalResearch.com (free)
A Review of Cancer Immunotherapy Toxicity
19 Jan, 2020 | 21:38h | UTCA review of cancer immunotherapy toxicity – CA: A Cancer Journal for Clinicians (free)
Related: Immune Checkpoint Inhibitor Toxicities (free guidelines and reviews on the subject)
The VITAMINS Randomized Clinical Trial: Vitamin C, Hydrocortisone, and Thiamine Not beneficial for Patients with Sepsis
19 Jan, 2020 | 21:44h | UTCEffect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Lack of Benefit of High-Dose Vitamin C, Thiamine, and Hydrocortisone Combination for Patients With Sepsis (free)
Conference Presentation: Effect of Vitamin C and Thiamine on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock (free)
Commentaries: JC: The Vitamins trial. Hydrocortisone, Vit C and Thiamine (Marik protocol – or not?) in sepsis – St Emlyn’s (free) AND Vitamin Treatment For Sepsis Fails In Large Trial – NPR (free) AND Metabolic Resuscitation: Was the answer inside us all along? – PulmCrit (free)
New Chinese virus ‘will have infected hundreds’
19 Jan, 2020 | 21:36h | UTCNew Chinese virus ‘will have infected hundreds’ – BBC (free)
Original Analysis: Estimating the potential total number of novel Coronavirus cases in Wuhan City, China – Imperial College London (free)
See also: Wuhan nCoV outbreak quadruples, spreads within China – CIDRAP (free) AND As Thailand notes 2nd nCoV case, CDC begins airport screening – CIDRAP (free) AND China reports new virus cases, raising concern globally before key holiday – Reuters (free) AND China to step up countermeasures as virus outbreak grows – Reuters (free) AND China Reports New Cases of Deadly Virus, Adding to Fears of Outbreak – The New York Times (10 articles per month are free)
Related Commentary on Twitter (Thread – Click for More)
Q: What can I do to protect myself from #coronavirus?
A: https://t.co/PKzKaO2yfK pic.twitter.com/eNhlhR0PEq
— World Health Organization (WHO) (@WHO) January 17, 2020
3-year Follow-up of the SCOT RCT: 3-month Oxaliplatin-containing Adjuvant Chemotherapy is Non-inferior to 6 Months of the Same Regimen for Patients with High-risk Stage II and III Colorectal Cancer
19 Jan, 2020 | 21:28h | UTCOriginal Article: 3 versus 6 months of adjuvant oxaliplatin-fluoropyrimidine combination therapy for colorectal cancer (SCOT): an international, randomised, phase 3, non-inferiority trial – The Lancet Oncology (free)
Source: EvidenceAlerts
Perspective: The EVALI and Youth Vaping Epidemics — Implications for Public Health
19 Jan, 2020 | 21:33h | UTCRelated: CDC: Vaping Lung Illness Probably Caused by Vitamin E Acetate (free resources)
[Abstract Only] Randomized Trial: Femtosecond Laser-Assisted vs. Phacoemulsification Cataract Surgery
19 Jan, 2020 | 21:26h | UTCFemtosecond laser-assisted versus phacoemulsification cataract surgery (FEMCAT): a multicentre participant-masked randomised superiority and cost-effectiveness trial – The Lancet (link to abstract – $ for full-text)
Position Statement: Mental Health Issues and Psychological Factors in Athletes
19 Jan, 2020 | 20:59h | UTCMental health issues and psychological factors in athletes: detection, management, effect on performance and prevention: American Medical Society for Sports Medicine Position Statement—Executive Summary – British Journal of Sports Medicine (free for a limited period)
Commentary: Sports Medicine Group Issues Guidance on Athletes’ Mental Health – Reuters / Medscape (free registration required)
Recommendations for the Management of Psoriatic Arthritis in Resource-poor Settings
19 Jan, 2020 | 21:01h | UTC
Addendum to BSH Guidelines on Investigation and Management of Antiphospholipid Syndrome: Use of Direct Acting Oral Anticoagulants
19 Jan, 2020 | 20:55h | UTCRelated: Randomized Trial: DOAC Not as Good as Vitamin K Antagonist for Anticoagulation in Antiphospholipid Syndrome (link to abstract and commentaries)
Position Statement on Endovascular Intervention for Trauma
19 Jan, 2020 | 20:57h | UTC
Meta-Analysis: The Socioeconomic Impact of Orthopedic Trauma
19 Jan, 2020 | 20:51h | UTCThe socioeconomic impact of orthopaedic trauma: A systematic review and meta-analysis – PLOS One (free)
Chest Radiography in Adult Critical Care Unit: A Pictorial Review
19 Jan, 2020 | 20:47h | UTC
Perspective: Are Polypills and Population-based Treatment the Next Big Things?
19 Jan, 2020 | 20:53h | UTCAre polypills and population-based treatment the next big things? – Harvard Health Blog (free)
Related: Randomized Trial: Polypill for Cardiovascular Disease Prevention in an Underserved Population (randomized trials, commentaries and guideline on the subject)
[Abstract Only] Cohort Study: Risk of Hypertension Into Adulthood in Persons Born Prematurely
19 Jan, 2020 | 20:46h | UTCRisk of hypertension into adulthood in persons born prematurely: a national cohort study – European Heart Journal (link to abstract – $ for full-text)
Source: EvidenceAlerts
Systematic Review: Economic Burden of Maternal Morbidity
19 Jan, 2020 | 20:49h | UTCEconomic burden of maternal morbidity – A systematic review of cost-of-illness studies – PLOS One (free)
Respiratory Muscle Ultrasonography: Methodology, Basic and Advanced Principles and Clinical Applications in ICU and ED Patients
19 Jan, 2020 | 20:42h | UTC
Cohort Study: Incidental Lymphopenia and Mortality
19 Jan, 2020 | 20:45h | UTCCommentaries: Lymphopenia may hint a higher risk of future illness, death – News Medical (free) AND Incidental Low Lymphocyte Count Linked to Increased Mortality – MedicalResearch.com (free)
What is New in Non-ventilated ICU-acquired Pneumonia?
19 Jan, 2020 | 20:41h | UTCWhat is new in non-ventilated ICU-acquired pneumonia? – Intensive Care Medicine (free)
[Abstract Only] Randomized Trial: Different Doses of Adjuvant Ipilimumab vs. High-Dose Interferon Alfa-2b in Patients with Resected High-Risk Melanoma
19 Jan, 2020 | 20:40h | UTCOriginal Study: Phase III Study of Adjuvant Ipilimumab (3 or 10 mg/kg) Versus High-Dose Interferon Alfa-2b for Resected High-Risk Melanoma: North American Intergroup E1609 – Journal of Clinical Oncology (link to abstract – $ for full-text)
Randomized Trial: Effect of Dasatinib vs. Imatinib in the Treatment of Pediatric Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia
19 Jan, 2020 | 20:38h | UTCEffect of Dasatinib vs Imatinib in the Treatment of Pediatric Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA Oncology (free for a limited period)
Commentary: Dasatinib Superior to Imatinib in Pediatric ALL – MedPage Today (free)
[Abstract Only] Randomized Trial: Lateral Extra-articular Tenodesis Reduces Failure of Hamstring Tendon Autograft Anterior Cruciate Ligament Reconstruction
19 Jan, 2020 | 20:34h | UTCLateral Extra-articular Tenodesis Reduces Failure of Hamstring Tendon Autograft Anterior Cruciate Ligament Reconstruction: 2-Year Outcomes From the STABILITY Study Randomized Clinical Trial – The American Journal of Sports Medicine (link to abstract – $ for full-text)
Related Commentary on Twitter
#StabilityStudy primary outcome published online. #LET reduces graft failure in young patents undergoing ACL reconstruction. @AJSM_SportsMed https://t.co/DHv1LxS8t2
— Al Getgood (@FKSMC_Getgood) January 15, 2020