Daily Archives: November 18, 2019 | LinksMedicus Free Medical News & Perspectives

#AHA19 – [Not Published Yet] Landmark ISCHEMIA Trial: A Routine Invasive Strategy Does Not Reduce Cardiovascular Events in Patients with Stable Coronary Artery Disease

18 Nov, 2019 | 01:13h | UTC

Commentaries: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches – ISCHEMIA – American College of Cardiology (free) AND ISCHEMIA Trial Examines Invasive vs. Conservative Strategy in SIHD Patients – American College of Cardiology (free) AND ISCHEMIA: Invasive Strategy No Better Than Meds for CV Events – TCTMD (free) AND Surgery for Blocked Arteries Is Often Unwarranted, Researchers Find – The New York Times (free) AND ISCHEMIA Trial Finds No Evidence of Lower Cardiac Event Rates in Patients Treated with Heart Procedures, but Better Quality of Life – PR Newswire (free) AND Big study casts doubt on need for many heart procedures – Associated Press (free) AND Stents no better than drugs for many heart patients: U.S. study – Reuters (free) AND Stents, bypass surgery show no benefit in heart disease mortality rates among stable patients – Stanford Medicine (free)

#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting

#AHA19 – [Abstract Only] Practice Changing? – Randomized Trial: Low-Dose Colchicine Improves Outcomes after Myocardial Infarction

18 Nov, 2019 | 01:11h | UTC

Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Colchicine Cardiovascular Outcomes Trial – COLCOT – American College of Cardiology (free) AND COLCOT Renews Hope for Anti-inflammatory in Secondary Prevention: Colchicine – TCTMD (free)

#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting

Related Commentary on Twitter

In a randomized, placebo-controlled trial of 4745 patients with recent myocardial infarction, low-dose colchicine (0.5 mg once daily) prevented ischemic cardiovascular events. See the COLCOT trial. #AHA19 https://t.co/H2eubZ6HRD

— NEJM (@NEJM) November 16, 2019

Mon November 18 – 10 Stories of The Day!

18 Nov, 2019 | 01:52h | UTC

1 – [Not Published Yet] Landmark ISCHEMIA Trial: A Routine Invasive Strategy Does Not Reduce Cardiovascular Events in Patients with Stable Coronary Artery Disease

Commentaries: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches – ISCHEMIA – American College of Cardiology (free) AND ISCHEMIA Trial Examines Invasive vs. Conservative Strategy in SIHD Patients – American College of Cardiology (free) AND ISCHEMIA: Invasive Strategy No Better Than Meds for CV Events – TCTMD (free) AND Surgery for Blocked Arteries Is Often Unwarranted, Researchers Find – The New York Times (free) AND ISCHEMIA Trial Finds No Evidence of Lower Cardiac Event Rates in Patients Treated with Heart Procedures, but Better Quality of Life – PR Newswire (free) AND Big study casts doubt on need for many heart procedures – Associated Press (free) AND Stents no better than drugs for many heart patients: U.S. study – Reuters (free) AND Stents, bypass surgery show no benefit in heart disease mortality rates among stable patients – Stanford Medicine (free)

#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting

2 – Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Colchicine Cardiovascular Outcomes Trial – COLCOT – American College of Cardiology (free) AND COLCOT Renews Hope for Anti-inflammatory in Secondary Prevention: Colchicine – TCTMD (free)

#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting

3 – Early Surgery or Conservative Care for Asymptomatic Aortic Stenosis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: RECOVERY Finds Early Surgery Beneficial For Asymptomatic Severe AS Patients – American College of Cardiology (free) AND Randomized Comparison of Early Surgery Versus Conventional Treatment in Very Severe Aortic Stenosis – RECOVERY – American College of Cardiology (free) AND Early Surgery Beats a Conservative Approach in Asymptomatic AS: RECOVERY – TCTMD (free)

#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting

4 – A Controlled Trial of Rivaroxaban after Transcatheter Aortic-Valve Replacement – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: GALILEO Trial Finds Higher Risk of Death, Bleeding With Rivaroxaban After TAVR – American College of Cardiology (free) AND Global Study Comparing a Rivaroxaban-based Antithrombotic Strategy to an Antiplatelet-based Strategy After TAVR – GALILEO – American College of Cardiology (free) AND GALILEO: Rivaroxaban-Based Antithrombotic Strategy or Antiplatelet-Based Strategy After TAVR? – Docwire (free)

#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting

5 – AHA Updates on Advanced Cardiovascular Life Support

– 2019 American Heart Association Focused Update on Advanced Cardiovascular Life Support: Use of Advanced Airways, Vasopressors, and Extracorporeal Cardiopulmonary Resuscitation During Cardiac Arrest – Circulation (free PDF)

– 2019 American Heart Association and American Red Cross Focused Update for First Aid: Presyncope – Circulation (free PDF)

– 2019 American Heart Association Focused Update on Systems of Care: Dispatcher-Assisted Cardiopulmonary Resuscitation and Cardiac Arrest Centers – Circulation (free PDF)

6 – AHA Updates in Pediatric Life Support

– 2019 American Heart Association Focused Update on Pediatric Advanced Life Support – Circulation (free PDF)

– 2019 American Heart Association Focused Update on Neonatal Resuscitation – Circulation (free PDF)

– 2019 American Heart Association Focused Update on Pediatric Basic Life Support – Circulation (free PDF)

7 – 2019 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces – Circulation (free PDF)

8 – Offline: The gravy train of systematic reviews – The Lancet (free)

9 – Moving Toward Evidence-Based Policy: The Value of Randomization for Program and Policy Implementation – JAMA (free for a limited period)

10 – Deep Brain Stimulation for Tinnitus, Tumors Hijack Neurons in Brain Cancer, and Multiple Sclerosis and Immunizations: Neuro Nook – JAMA (free for a limited period)

#AHA19 – [Abstract Only] Randomized Trial: An Antiplatelet-based Strategy is Associated with Better Outcomes vs. Anticoagulation After Transcatheter Aortic-Valve Replacement

18 Nov, 2019 | 01:08h | UTC

A Controlled Trial of Rivaroxaban after Transcatheter Aortic-Valve Replacement – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: GALILEO Trial Finds Higher Risk of Death, Bleeding With Rivaroxaban After TAVR – American College of Cardiology (free) AND Global Study Comparing a Rivaroxaban-based Antithrombotic Strategy to an Antiplatelet-based Strategy After TAVR – GALILEO – American College of Cardiology (free) AND GALILEO: Rivaroxaban-Based Antithrombotic Strategy or Antiplatelet-Based Strategy After TAVR? – Docwire (free)

#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting

Related Commentary on Twitter

Patients who had had successful TAVR randomized to either a rivaroxaban-based antithrombotic regimen or an antiplatelet-based regimen. At 17 mos, death or thromboembolic complications occurred more frequently w/ rivaroxaban. See the GALILEO trial. #AHA19 https://t.co/boQo9SbGKe

— NEJM (@NEJM) November 16, 2019

AHA Updates on Advanced Cardiovascular Life Support (ACLS)

18 Nov, 2019 | 01:00h | UTC

– 2019 American Heart Association and American Red Cross Focused Update for First Aid: Presyncope – Circulation (free PDF)

– 2019 American Heart Association Focused Update on Systems of Care: Dispatcher-Assisted Cardiopulmonary Resuscitation and Cardiac Arrest Centers – Circulation (free PDF)

#AHA19 – [Abstract Only] Randomized Trial: Early Surgery Improves Outcomes in Asymptomatic Patients with Very Severe Aortic Stenosis

18 Nov, 2019 | 01:09h | UTC

Early Surgery or Conservative Care for Asymptomatic Aortic Stenosis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: RECOVERY Finds Early Surgery Beneficial For Asymptomatic Severe AS Patients – American College of Cardiology (free) AND Randomized Comparison of Early Surgery Versus Conventional Treatment in Very Severe Aortic Stenosis – RECOVERY – American College of Cardiology (free) AND Early Surgery Beats a Conservative Approach in Asymptomatic AS: RECOVERY – TCTMD (free)

#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting

Related Commentary on Twitter

At a median of 6 years of follow-up, operative mortality or CV death occurred less frequently in asymptomatic patients with very severe aortic stenosis who received early valve replacement surgery than in those conservatively managed. #AHA19 https://t.co/hcQeoRqseJ

— NEJM (@NEJM) November 16, 2019