Daily Archives: September 15, 2019
Meta-Analysis: Parenteral Methotrexate Better Than Oral MTX for Achieving Reduction in Disease Activity in Patients with Rheumatoid Arthritis
15 Sep, 2019 | 23:59h | UTCCommentary: Rheumatoid arthritis: parenteral MTX tops pills for efficacy – Univadis (free registration required)
Viewpoint: Redefining Heart Failure with a Reduced Ejection Fraction
15 Sep, 2019 | 23:46h | UTCRedefining Heart Failure With a Reduced Ejection Fraction – JAMA (free for a limited period)
European Guidelines on Endoscopic Management of Polyposis Syndromes
15 Sep, 2019 | 23:58h | UTC
Systematic Review: Strategies to Reduce Diagnostic Errors
15 Sep, 2019 | 23:44h | UTCRelated: Discover and defeat your diagnostic errors – ACP Internist (free)
[Abstract Only] Study: Liquid vs. Tissue Biopsy for Detecting Acquired Resistance and Tumor Heterogeneity in Gastrointestinal Cancers
15 Sep, 2019 | 23:41h | UTCLiquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers – Nature Medicine (link to abstract – $ for full-text)
Commentary: Liquid biopsies reveal genetic alterations linked to cancer drug resistance – Broad Institute of MIT and Harvard (free)
Related Commentary on Twitter
6 words not often seen in top tier journals: "These findings have profound therapeutic implications …and highlight the potential advantages of cfDNA [liquid biopsy] over tissue biopsy in the setting of acquired [#cancer] resistance.https://t.co/92gF4OX10H @NatureMedicine pic.twitter.com/mj0NQC17SP
— Eric Topol (@EricTopol) September 10, 2019
Evaluation and Management of Angioedema in the Emergency Department
15 Sep, 2019 | 23:43h | UTCSource: Medscape
Study: Progress in Cancer Survival, Mortality, and Incidence in Seven High-income Countries 1995–2014
15 Sep, 2019 | 23:35h | UTCCommentaries: Cancer Patients in Rich Countries Are Gaining Years, Study Shows – Bloomberg (free) AND Cancer survival in high income countries is improving but international disparities persist – eCancer News (free)
Related Commentary on Twitter
1-yr & 5-yr survival of seven #cancers (oesophagus, stomach, colon, rectum, pancreas, lung & ovary) improved in Australia, Canada, Denmark, Ireland, New Zealand, Norway & UK: SURVMARK-2 study of 3.9m cancer cases 1995-2014 @IARCWHO https://t.co/NqWmKl5T6R pic.twitter.com/xhmIpCwflq
— The Lancet Oncology (@TheLancetOncol) September 11, 2019
[Abstract Only] What’s the Right Pediatric ETT Size?
15 Sep, 2019 | 23:37h | UTCWhat’s the Right Pediatric ETT Size? – Journal Feed (free)
Original Article: Tracheal Size and Morphology on the Reconstructed CT Imaging – Pediatric Critical Care Medicine (link to abstract – $ for full-text)
Updates in Pathophysiology, Definition and Classification of Hepatorenal Syndrome
15 Sep, 2019 | 23:34h | UTCNews in pathophysiology, definition and classification of hepatorenal syndrome: A step beyond the International Club of Ascites (ICA) consensus document – Journal of Hepatology (free for a limited period)
Related Article: Diagnosis and management of acute kidney injury in patients with cirrhosis: revised consensus recommendations of the International Club of Ascites – Gut (free PDF)
Related Guidelines: Cirrhosis in Over 16s: Assessment and Management – National Institute for Health and Care Excellence (free) AND 2018 KASL clinical practice guidelines for liver cirrhosis: Ascites and related complications – Clinical and Molecular Hepatology (free) AND 2018 Recommendations of the Brazilian Society of Hepatology for the management of acute kidney injury in patients with cirrhosis (free PDF) AND Evidence-based clinical practice guidelines for liver cirrhosis 2015 – Journal of Gastroenterology (free) AND Chinese guidelines on the management of ascites and its related complications in cirrhosis – Hepatology International (free)
[Abstract Only] Study: Few People with Peanut Allergy Tolerate Peanut After Stopping Oral Immunotherapy
15 Sep, 2019 | 23:32h | UTCFew people with peanut allergy tolerate peanut after stopping oral immunotherapy – NIH News Releases (free)
Original Study: Sustained outcomes in oral immunotherapy for peanut allergy (POISED study): a large, randomised, double-blind, placebo-controlled, phase 2 study – The Lancet (link to abstract – $ for full-text)
Related: Meta-Analysis: Oral Immunotherapy for Peanut Allergy INCREASES Allergic and Anaphylactic Reactions (link to abstract and commentaries)