Daily Archives: January 9, 2019 | LinksMedicus Free Medical News & Perspectives

“The current evidence from clinical trials suggests neither clear benefits nor clear harms from the use of short‐acting insulin analogues over regular human insulin.”

Comparative Safety and Effectiveness of Treatments for Alzheimer’s Disease

9 Jan, 2019 | 22:10h | UTC

Comparative safety and effectiveness of cholinesterase inhibitors and memantine for Alzheimer’s disease: a network meta-analysis of 41 randomized controlled trials – Alzheimer’s Research & Therapy (free)

Association Between Surrogate End-points and Overall Survival in Oncology

9 Jan, 2019 | 22:45h | UTC

A systematic review of trial-level meta-analyses measuring the strength of association between surrogate end-points and overall survival in oncology – European Journal of Cancer (free for a limited period)

“we found most surrogates in oncology had low or modest correlation with OS, which suggests that caution should be used when making conclusions based on surrogate markers.”

Pregnancy After Bariatric Surgery: Impact on Pregnancy Management and Outcome

9 Jan, 2019 | 17:32h | UTC

Pregnancy after bariatric surgery: a narrative literature review and discussion of impact on pregnancy management and outcome – BMC Pregnancy and Childbirth (free)

Review: Eliminating Neglected Tropical Diseases in Urban Areas

9 Jan, 2019 | 21:59h | UTC

Eliminating Neglected Tropical Diseases in Urban Areas: A Review of Challenges, Strategies and Research Directions for Successful Mass Drug Administration – Tropical Medicine and Infectious Diseases (free)

AAN Calls for Uniformity of Brain Death Determination

9 Jan, 2019 | 16:34h | UTC

Brain death, the determination of brain death, and member guidance for brain death accommodation requests: AAN position statement – Neurology (free PDF)

News Release: AAN Calls for Uniformity of Brain Death Determination (free)

Commentary: Neurology Group: Universal Definition of Brain Death Needed -NEJM Journal Watch (free)

Guideline: Pregnancy in Multiple Sclerosis

9 Jan, 2019 | 12:03h | UTC

UK consensus on pregnancy in multiple sclerosis: ‘Association of British Neurologists’ guidelines – Practical Neurology (free)

Proton Pump Inhibitors: Review of Reported Risks and Controversies

9 Jan, 2019 | 16:40h | UTC

Proton pump inhibitors: Review of reported risks and controversies – Laryngoscope Investigative Otolaryngology (free)

Related: Proton Pump Inhibitors: Review of Emerging Concerns (free reviews) AND Deprescribing Proton Pump Inhibitors (free guidelines and reviews)

Systematic Review: Iron for the Treatment of Restless Legs Syndrome

9 Jan, 2019 | 16:19h | UTC

Iron for the treatment of restless legs syndrome – Cochrane Library (free)

Summary: Iron for the treatment of restless legs syndrome – Cochrane Library (free)

High-Performance Medicine: The Convergence of Human and Artificial Intelligence

9 Jan, 2019 | 11:26h | UTC

High-performance medicine: the convergence of human and artificial intelligence – Nature Medicine (free for 30 days)

NCCN Guideline: Thyroid Carcinoma

9 Jan, 2019 | 09:56h | UTC

NCCN Guidelines Insights: Thyroid Carcinoma, Version 2.2018 – Journal of the National Comprehensive Cancer Network (free)

Guidelines for Performing a Comprehensive Transthoracic Echocardiographic Examination in Adults

9 Jan, 2019 | 10:12h | UTC

Guidelines for Performing a Comprehensive Transthoracic Echocardiographic Examination in Adults: Recommendations from the American Society of Echocardiography – Journal of the American Society of Echocardiography (free)

Reverse Takotsubo Cardiomyopathy: A Comprehensive Review

9 Jan, 2019 | 07:40h | UTC

Reverse Takotsubo cardiomyopathy: a comprehensive review – Annals of Translational Medicine (free)

NCCN Guideline: Systemic Mastocytosis

9 Jan, 2019 | 08:48h | UTC

Systemic Mastocytosis, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network (free)

What We Learned in 2018: Health and Medicine

9 Jan, 2019 | 06:57h | UTC

What We Learned in 2018: Health and Medicine – The New York Times (10 articles per month are free)

Systematic Review: Long-Term Prognosis and Outcome Predictors in Takotsubo Syndrome

9 Jan, 2019 | 07:51h | UTC

Long-Term Prognosis and Outcome Predictors in Takotsubo Syndrome: A Systematic Review and Meta-Regression Study – JACC: Heart Failure (link to abstract – $ for full-text)

Commentary: Takotsubo Syndrome Not Necessarily ‘Benign’ or Fleeting – TCTMD (free)

Related Studies: Hospital Readmission Following Takotsubo Syndrome (link to abstract and commentaries) AND International Registry: Long-Term Prognosis of Patients With Takotsubo Syndrome (link to abstract and commentaries)

The Health of The World In 2018, By The Numbers

9 Jan, 2019 | 05:31h | UTC

The Health of The World In 2018, By The Numbers – NPR Goats and Soda (free)

Wed, January 9 – 10 Stories of The Day!

9 Jan, 2019 | 00:01h | UTC

1 – The Year in Cardiology 2018 – European Heart Journal (free articles)

– Prevention

– Acute Coronary Syndromes

– Arrhythmias and Cardiac Devices

– Valvular Heart Disease

– Aorta and Peripheral Circulation

– Imaging

2 – Guideline: Renal and ureteric stones: assessment and management – National Institute for Health and Care Excellence (free)

3 – Routine preoperative medical testing for cataract surgery – Cochrane Library (free)

Summary: Routine preoperative medical testing for cataract surgery – Cochrane Library (free)

“This review has shown that routine preoperative testing does not increase the safety of cataract surgery.”

4 – Keep O2 saturations at 96% or below for hospitalized patients: expert panel – PulmCC (free)

Original Article: Oxygen therapy for acutely ill medical patients: a clinical practice guideline – The BMJ (free study and commentary)

5 – Point and Counterpoint: Should the Surviving Sepsis Campaign Guidelines Be Retired?

POINT: Should the Surviving Sepsis Campaign Guidelines Be Retired? Yes – Chest (free)

COUNTERPOINT: Should the Surviving Sepsis Campaign Guidelines Be Retired? No – Chest (free)

Related: The 2018 Surviving Sepsis Campaign’s Treatment Bundle: When Guidelines Outpace the Evidence Supporting Their Use (free guideline and commentaries)

6 – Will the world embrace Plan S, the radical proposal to mandate open access to science papers? – Science (free)

7 – SEOM clinical guidelines to primary prevention of cancer (2018) – Clinical and Translational Oncology (free)

8 – Operative treatment versus nonoperative treatment of Achilles tendon ruptures: systematic review and meta-analysis – The BMJ (free)

Commentaries: Surgeons should know when not to operate – The BMJ Opinion (free) AND Surgery or Not for Achilles Rupture? Meta-Analysis Finds Mixed Bag – NEJM Journal Watch (free)

9 – Identifying facial phenotypes of genetic disorders using deep learning – Nature Medicine (link to abstract – $ for full-text)

Commentaries: AI face-scanning app spots signs of rare genetic disorders – Nature News (free) AND Artificial intelligence could diagnose rare disorders using just a photo of a face – Science Magazine (free)

10 – Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life – Cochrane Library (free)

Summary: Vitamin and mineral supplementation for preventing cognitive deterioration in cognitively healthy people in mid and late life – Cochrane Library (free)

Commentary: Preventing dementia: do vitamin and mineral supplements have a role? – Evidently Cochrane (free)

10 of the Best Articles in Emergency Medicine from 2018

9 Jan, 2019 | 06:12h | UTC

10 of the Best Medical Journal Articles from 2018 – ACEP Now (free)

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