Daily Archives: October 25, 2018

Thu, October 25 – 10 Stories of The Day!

25 Oct, 2018 | 00:01h | UTC

 

1 – Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU – New England Journal of Medicine (free for a limited period)

Editorial: Proton-Pump Inhibitor Prophylaxis in the ICU — Benefits Worth the Risks? (free for a limited period)

“Proton pump inhibitors are minimally effective to reduce GI bleeding among the critically ill folks at high risk for stress ulcers. Takeaways: no role for routine PPI for any patients on the WARDS, and shouldn’t be considered ‘routine’ in the ICU” (via @AnilMakam see Tweet)

 

2 – Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients with Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Hypothermia After Traumatic Brain Injury (free)

Commentary: Hypothermia for Severe TBI Called into Question – NEJM Journal Watch (free)

 

3 – Effect of a Low vs Intermediate Tidal Volume Strategy on Ventilator-Free Days in Intensive Care Unit Patients Without ARDS: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Lessons From ARDS for Non-ARDS Research: Remembrance of Trials Past (free)

“Among patients in the ICU receiving invasive ventilation, a strategy with low tidal volume was not more effective than a strategy using intermediate tidal volume.”

 

4 – Association of Weather with Day-to-Day Incidence of Myocardial Infarction: A SWEDEHEART Nationwide Observational Study – JAMA Cardiology (free)

Commentaries: Your risk of a heart attack could increase as it gets colder, study says – CNN (free) AND Cold, cloudy weather ‘could increase your risk of having heart attack’ – The Guardian (free)

 

5 – Average Clinician‐Measured Blood Pressures and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus and Ischemic Heart Disease in the EXAMINE Trial – Journal of the American Heart Association (free)

Editorial: The Ongoing Saga of Optimal Blood Pressure Level in Patients With Diabetes Mellitus and Coronary Artery Disease (free)

“A U‐shaped relationship between cardiovascular outcomes and BPs was observed.”

 

6 – Association of Blood Pressure Measurements With Peripheral Artery Disease Events: Reanalysis of the ALLHAT Data – Circulation (free)

Editorial: New Curveball for Hypertension Guidelines? Blood Pressure Targets in Peripheral Artery Disease (free)

“we found a higher rate of lower extremity PAD events with higher and lower SBP and pulse pressure and with lower DBP.”

 

7 – Clinical Model to Predict 90-Day Risk of Readmission After Acute Myocardial Infarction: A Report From the National Cardiovascular Data Registry ACTION Registry – Circulation: Cardiovascular Quality and Outcomes (free)

Commentaries: Score predicts 90-day readmission risk after myocardial infarction – ACP Hospitalist (free) AND Novel risk predictor identifies likelihood of readmission after AMI – Cardiovascular Business (free)

 

8 – Review: Pulmonary Embolism: Contemporary Medical Management and Future Perspectives – Annals of Vascular Disease (free PDF)

 

9 – Canadian Urological Association guideline on male lower urinary tract symptoms/benign prostatic hyperplasia (MLUTS/BPH): 2018 update – Canadian Urological Association Journal (free)

Related Guideline: Surgical Management of Lower Urinary Tract Symptoms attributed to BPH (free guideline and commentary)

 

10 – Self-monitoring of blood glucose provides no important benefit for most people with type 2 diabetes – NIHR Signal (free)

Original Article: Self-monitoring blood glucose improves glycemic control in type 2 diabetes without intensive treatment: A systematic review and meta-analysis – Diabetes Research and Clinical Practice (link to abstract – $ for full-text)

 

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