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Daily Archives: April 24, 2018

World Immunization Week, 24-30 April 2018 – World Health Organization

24 Apr, 2018 | 19:34h | UTC

World Immunization Week, 24-30 April 2018 – World Health Organization (free resources)

 


The Vaccine Dilemma: How Experts Weigh Benefits for Many Against Risks for a Few

24 Apr, 2018 | 19:34h | UTC

The vaccine dilemma: how experts weigh benefits for many against risks for a few – STAT (free)

 


Richard Lehman’s journal review – 23 April 2018

24 Apr, 2018 | 19:31h | UTC

Richard Lehman’s journal review, 23 April 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

 


AAN Guideline: Disease-modifying Therapies for Adults with Multiple Sclerosis

24 Apr, 2018 | 19:33h | UTC

Practice guideline recommendations summary: Disease-modifying therapies for adults with multiple sclerosis – Neurology (free)

See also: Related Physician Tools and Materials (free clinician summary, slides and more)

Commentaries: New guideline: Start taking MS drugs early on – American Academy of Neurology, via EurekAlert (free)

New MS Guideline Addresses Starting, Switching, and Stopping Disease-modifying Therapy – MD Magazine (free) AND Start MS Drugs Early, New Guideline Says – MedPage Today (free registration required)

 


Meta-Analysis: Procalcitonin-Guidance vs Usual Care for Antimicrobial Management in Critically Ill Patients

24 Apr, 2018 | 18:05h | UTC

Systematic Review and Meta-Analysis of Procalcitonin-Guidance Versus Usual Care for Antimicrobial Management in Critically Ill Patients: Focus on Subgroups Based on Antibiotic Initiation, Cessation, or Mixed Strategies – Critical Care Medicine (free)

Related Meta-Analysis: Efficacy and Safety of Procalcitonin Guidance in Patients With Suspected or Confirmed Sepsis: A Systematic Review and Meta-Analysis – Critical Care Medicine (free)

Commentaries: Cessation, not initiation, of antibiotics is when procalcitonin guidance cuts mortality – Univadis (free registration required) AND Procalcitonin guidance reduces antibiotic duration in critically ill adults: meta-analysis – Univadis (free)

 


Cohort Study: Proton‐Pump Inhibitors and Risk of Pneumonia in Older Adults

24 Apr, 2018 | 19:29h | UTC

Proton‐Pump Inhibitors and Long‐Term Risk of Community‐Acquired Pneumonia in Older Adults – Journal of the American Geriatrics Society (free)

Commentary: Commonly prescribed heartburn drug linked to Pneumonia in Older Adults – University of Exeter (free)

Related: Proton Pump Inhibitors: Review of Emerging Concerns – Mayo Clinic Proceedings (free) AND Complications of Proton Pump Inhibitor Therapy – Gastroenterology (free) AND Adverse effects of proton-pump inhibitor use in older adults: a review of the evidence – Therapeutic Advances in Drug Safety (free) AND Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free)

Source: Hospital Medicine Virtual Journal Club

 


Review: Cardiovascular Risk in Patients with Rheumatoid Arthritis

24 Apr, 2018 | 19:31h | UTC

State of the Art Review: Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications – The BMJ (free for a limited period)

 


Research: Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma

24 Apr, 2018 | 18:04h | UTC

Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Study reveals subtypes of lymphoma – NIH Research Matters (free)

 


Perspective: The Blind Men and the Elephant — Aligning Efforts in Global Health

24 Apr, 2018 | 18:03h | UTC

Perspective: The Blind Men and the Elephant — Aligning Efforts in Global Health – New England Journal of Medicine (free)

 


Review: Management of Dyspnea in the Terminally Ill

24 Apr, 2018 | 18:03h | UTC

Management of Dyspnea in the Terminally Ill – CHEST (free PDF)

Source: Hospital Medicine Virtual Journal Club

 


Research: Antibiotic Use After Removal of Penicillin Allergy Label

24 Apr, 2018 | 18:04h | UTC

Antibiotic Use After Removal of Penicillin Allergy Label – Pediatrics (link to abstract – $ for full-text)

Commentaries: Penicillin Allergy Testing Could Save Money, Improve Care – American Academy of Pediatrics (free) AND Delabeling for Penicillin Allergy Found Safe in Children – Medscape (free registration required) AND Removing penicillin allergy label from kids saves antibiotics, money – CIDRAP, in Resistance Scan for Apr 20, 2018 (free)

 


Meta-Analysis: Premenstrual Syndrome and Alcohol Consumption

24 Apr, 2018 | 18:00h | UTC

Premenstrual syndrome and alcohol consumption: a systematic review and meta-analysis – BMJ Open (free)

Commentaries: Drinking alcohol linked to higher risk of PMS – OnMedica (free) AND Heavy drinking linked to worse PMS – Reuters (free)

 


Randomized Controlled Trial: Home vs Hospital Treatment of COPD Exacerbation

24 Apr, 2018 | 18:01h | UTC

Home treatment of COPD exacerbation selected by DECAF score: a non-inferiority, randomised controlled trial and economic evaluation -Thorax (free)

Source: Hospital Medicine Virtual Journal Club

 


Systematic Review: Antifibrinolytics for Heavy Menstrual Bleeding

24 Apr, 2018 | 17:58h | UTC

Antifibrinolytics for heavy menstrual bleeding – Cochrane Library (link to abstract and summary)

“Antifibrinolytics appear effective tor treating for heavy menstrual bleeding, without substantially increasing the rate of adverse events” (via @CochraneLibrary see Tweet)

 


Expert Analysis: Major Dyslipidemia Guidelines and Their Discrepancies

24 Apr, 2018 | 17:58h | UTC

Major Dyslipidemia Guidelines and Their Discrepancies: A Need for Consensus – American College of Cardiology (free)

 


FDA Approves Rapid Diagnostic Test for Candida Auris

24 Apr, 2018 | 17:57h | UTC

FDA approves rapid diagnostic test for Candida auris – CIDRAP (free)

FDA News Release: FDA authorizes new use of test, first to identify the emerging pathogen Candida auris (free)

Related: Tracking Candida auris – CDC (free)

 

 


Review: The Vasculature in Prediabetes

24 Apr, 2018 | 17:59h | UTC

The Vasculature in Prediabetes – Circulation Research (free for a limited period) (via @Abraham_RMI)

 


Tue, April 24 – 10 Stories of The Day!

24 Apr, 2018 | 01:43h | UTC

 

1 – World Immunization Week, 24-30 April 2018 – World Health Organization (free resources)

 

2 – The vaccine dilemma: how experts weigh benefits for many against risks for a few – STAT (free)

 

3 – Why do we need vaccines? – Welcome Trust (free) (via @greg_folkers)

 

4 – Exercise after a heart attack — it could save your life, research suggests – European Society of Cardiology, via ScienceDaily (free)

Other commentaries: Regular exercise after heart attack might halve risk of death over next few years – OnMedica (free) AND It’s not too late: Exercise after heart attack cuts mortality risk – Cardiovascular Business (free) AND Remaining Active After MI May Help Stave Off Mortality – TCTMD (free)

“Becoming more physically active after a myocardial infarction halves the risk of dying within 4 years, study finds”

 

5 – Safety and efficacy of dual vs. triple antithrombotic therapy in patients with atrial fibrillation following percutaneous coronary intervention: a systematic review and meta-analysis of randomized clinical trials – European Heart Journal (free)

“Compared with triple antithrombotic therapy, dual antithrombotic therapy shows a reduction in major or minor bleeding by 47% with comparable outcomes of major adverse cardiac events”.

 

6 – Practice guideline recommendations summary: Disease-modifying therapies for adults with multiple sclerosis – Neurology (free)

See also: Related Physician Tools and Materials (free clinician summary, slides and more)

Commentaries: New guideline: Start taking MS drugs early on – American Academy of Neurology, via EurekAlert (free) AND New MS Guideline Addresses Starting, Switching, and Stopping Disease-modifying Therapy – MD Magazine (free) AND Start MS Drugs Early, New Guideline Says – MedPage Today (free registration required)

 

7 – Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV – AIDSInfo (free)

 

8 – Richard Lehman’s journal review, 23 April 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

 

9 – State of the Art Review: Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications – The BMJ (free for a limited period)

 

10 – Proton‐Pump Inhibitors and Long‐Term Risk of Community‐Acquired Pneumonia in Older Adults – Journal of the American Geriatrics Society (free)

Commentary: Commonly prescribed heartburn drug linked to Pneumonia in Older Adults – University of Exeter (free)

Related: Proton Pump Inhibitors: Review of Emerging Concerns – Mayo Clinic Proceedings (free) AND Complications of Proton Pump Inhibitor Therapy – Gastroenterology (free) AND Adverse effects of proton-pump inhibitor use in older adults: a review of the evidence – Therapeutic Advances in Drug Safety (free) AND Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free)

Source: Hospital Medicine Virtual Journal Club

 


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